Modafinil and Tradjenta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Modafinil (modafinil) and Tradjenta (linagliptin). Common drug interactions include swelling among females and malaise among males.
The phase IV clinical study analyzes what interactions people have when they take Modafinil and Tradjenta. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Modafinil?
Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
30 people who take Modafinil and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Modafinil and Tradjenta, by gender? *:
female:
- Swelling
- Vulval cancer
- Fall
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Blood cholesterol decreased
- Death
- Somnambulism (sleep walking)
- Arrhythmia (irregular heartbeat)
- Blood sodium increased
male:
- Malaise (a feeling of general discomfort or uneasiness)
- Anaemia (lack of blood)
- Lumbar vertebral fracture
- Personality change
- Vomiting
- Drug ineffective
- Vitamin d decreased
- Abnormal behaviour
- Ankle fracture
- Dizziness
What are the common drug interactions of Modafinil and Tradjenta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Epistaxis (bleed from the nose)
- Nausea (feeling of having an urge to vomit)
- Paranasal cyst (cyst near the nose)
- Abdominal pain upper
- Adhesion
- Arthralgia (joint pain)
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- Bladder disorder
- Breast mass
- Burning sensation
50-59:
- Anaemia (lack of blood)
- Drug ineffective
- Malaise (a feeling of general discomfort or uneasiness)
- Vitamin d decreased
- Blood cholesterol decreased
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Somnambulism (sleep walking)
- Swelling
- Cataplexy (loss of muscle tone accompanied by full conscious awareness)
- Abnormal behaviour
60+:
- Arrhythmia (irregular heartbeat)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Arthralgia (joint pain)
- Blood cholesterol increased
- Dizziness
- Fall
- Hallucination (an experience involving the perception of something not present)
- Limb injury
- Lumbar vertebral fracture
- Malaise (a feeling of general discomfort or uneasiness)
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 26.67%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 20.00%
- Sleep Disorder: 3 people, 10.00%
- Pain: 3 people, 10.00%
- Anaemia (lack of blood): 3 people, 10.00%
- Sleep Apnea Syndrome: 2 people, 6.67%
- Irritability: 2 people, 6.67%
- High Blood Pressure: 2 people, 6.67%
- High Blood Cholesterol: 2 people, 6.67%
- Dry Eyes (lack of adequate tears): 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Modafinil and Tradjenta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Modafinil and Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Modafinil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Modafinil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tradjenta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on modafinil and linagliptin (the active ingredients of Modafinil and Tradjenta, respectively), and Modafinil and Tradjenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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