Morphine and Brilinta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Brilinta (ticagrelor). Common drug interactions include blood cholesterol increased among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Brilinta. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Brilinta?

Brilinta has active ingredients of ticagrelor. It is often used in stent. eHealthMe is studying from 22,469 Brilinta users. Check the latest studies of Brilinta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

97 people who take Morphine and Brilinta together, and have interactions are studied.

Morphine and Brilinta drug interactions.

What are the common drug interactions of Morphine and Brilinta, by gender? *:

female:

Blood cholesterol increased
Bundle branch block (disruption in the normal flow of electrical pulses that drive the heart beat)
Chest pain
Depressed mood
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
General physical condition
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

male:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Dysuria (painful or difficult urination)
Gastric disorder (disease of stomach)
Gastric ulcer (stomach ulcer)
Limb discomfort (discomfort in leg)
Palpitations (feelings or sensations that your heart is pounding or racing)
Viral diarrhoea
Vomiting
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

What are the common drug interactions of Morphine and Brilinta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac fibrillation (uncontrolled muscle contraction of heart)
Abdominal distension
Activated partial thromboplastin time prolonged
Bilirubin conjugated increased
Blood bilirubin increased
Bradycardia (abnormally slow heart action)
Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
Brain midline shift
Cerebral haemorrhage (bleeding within the brain)
Dementia (madness)

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haematochezia (passage of stools containing blood)
Incontinence (lack of moderation or self-control)
Vomiting
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Alopecia (absence of hair from areas of the body)
Chronic kidney disease
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)

50-59:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Chest pain
Abdominal distension
Acute myocardial infarction (acute heart attack)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Coronary artery stenosis (narrowing of coronary artery)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Adverse event

60+:

Dyspnoea (difficult or laboured respiration)
Chronic kidney disease
Renal cancer (cancer of kidney)
Drug hypersensitivity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Cardiac failure acute
Asthenia (weakness)
Death
Hypertension (high blood pressure)
Hypertransaminasaemia

What are the existing conditions these people have? *

High Blood Cholesterol: 11 people, 11.34%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.31%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 10 people, 10.31%
High Blood Pressure: 9 people, 9.28%
Depression: 9 people, 9.28%
Blood Pressure Abnormal: 9 people, 9.28%
Multiple Myeloma (cancer of the plasma cells): 8 people, 8.25%
Stress And Anxiety: 7 people, 7.22%
Cardiac Disorder: 6 people, 6.19%
Type 2 Diabetes: 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

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