Morphine and Cambia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Cambia (diclofenac potassium). Common drug interactions include abdominal wall haematoma among females and blindness among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Cambia. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Cambia?

Cambia has active ingredients of diclofenac potassium. eHealthMe is studying from 2,339 Cambia users. Check the latest studies of Cambia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

30 people who take Morphine and Cambia together, and have interactions are studied.

Morphine and Cambia drug interactions.

What are the common drug interactions of Morphine and Cambia, by gender? *:

female:

  1. Abdominal wall haematoma (abdominal wall blood clotting)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Blood calcium decreased
  4. Blood creatine phosphokinase increased
  5. Blood glucose increased
  6. Blood phosphorus increased
  7. Blood urea decreased
  8. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  9. Carbon dioxide decreased
  10. Faecaloma (hard mass of fecal matter)

male:

  1. Blindness
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Fall
  4. Foot fracture
  5. Migraine (headache)
  6. Photopsia (presence of perceived flashes of light)
  7. Tunnel vision (the loss of peripheral vision with retention of central vision)
  8. Vision blurred
  9. Visual field defect

What are the common drug interactions of Morphine and Cambia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Mononeuritis (single nerve damage)
  2. Muscle spasms (muscle contraction)
  3. Myalgia (muscle pain)
  4. Myositis (inflammation of the muscles)
  5. Nerve compression
  6. Pancreatitis (inflammation of pancreas)
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Poor quality sleep
  9. Post laminectomy syndrome
  10. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

50-59:

  1. Abdominal hernia
  2. Abdominal wall haematoma (abdominal wall blood clotting)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Blood calcium decreased
  5. Blood creatine phosphokinase increased
  6. Blood glucose increased
  7. Blood phosphorus increased
  8. Blood urea decreased
  9. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  10. Carbon dioxide decreased

60+:

  1. Abdominal hernia
  2. Abdominal wall haematoma (abdominal wall blood clotting)
  3. Faecaloma (hard mass of fecal matter)
  4. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  5. Haemorrhage (bleeding)
  6. Hypotension (abnormally low blood pressure)
  7. Iron deficiency anaemia
  8. Jugular vein thrombosis (clot in jugular vein)
  9. Leukopenia (less number of white blood cells in blood)
  10. Lymphocyte count decreased

What are the existing conditions these people have? *

  1. Migraine (headache): 10 people, 33.33%
  2. Nausea (feeling of having an urge to vomit): 8 people, 26.67%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 26.67%
  4. Headache (pain in head): 7 people, 23.33%
  5. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 6 people, 20.00%
  6. Insomnia (sleeplessness): 6 people, 20.00%
  7. Chest Pain: 6 people, 20.00%
  8. Dehydration (dryness resulting from the removal of water): 6 people, 20.00%
  9. Electrolyte Imbalance: 6 people, 20.00%
  10. Fever: 6 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Morphine and Cambia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Morphine and Cambia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cambia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cambia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and diclofenac potassium (the active ingredients of Morphine and Cambia, respectively), and Morphine and Cambia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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