Morphine and Canagliflozin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Morphine (morphine sulfate) and Canagliflozin (canagliflozin). Common drug interactions include gait disturbance among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Morphine and Canagliflozin. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,914 Morphine users. Check the latest studies of Morphine.

What is Canagliflozin?

Canagliflozin has active ingredients of canagliflozin. eHealthMe is studying from 3,253 Canagliflozin users. Check the latest studies of Canagliflozin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

31 people who take Morphine and Canagliflozin together, and have interactions are studied.

Morphine and Canagliflozin drug interactions.

What are the common drug interactions of Morphine and Canagliflozin, by gender? *:

female:

Gait disturbance
Arthralgia (joint pain)
Blood glucose increased
Blood pressure increased
Bone pain
Chronic kidney disease
Cough
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

male:

Neutropenia (an abnormally low number of neutrophils)
Vomiting
Osteomyelitis (infection of bone)
Pneumonia
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Skin ulcer
Abdominal distension
Abscess limb (limb infection)
Anal abscess
Arrhythmia (irregular heartbeat)

What are the common drug interactions of Morphine and Canagliflozin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ketosis (a state of elevated levels of ketone bodies in the body)
Polyuria (production of too much dilute urine)

40-49:

Rectal haemorrhage (bleeding from anus)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Pancreatitis (inflammation of pancreas)
Vomiting

50-59:

Diabetic foot infection
Infection
Osteomyelitis (infection of bone)
Skin ulcer
Nausea (feeling of having an urge to vomit)

60+:

Gait disturbance
Neutropenia (an abnormally low number of neutrophils)
Joint swelling
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Muscular weakness (muscle weakness)
Pain in extremity
Rales (an abnormal respiratory sound characterized by fine crackles)
Restless legs syndrome (a powerful urge to move your legs)
Sleep disorder
Weight increased

What are the existing conditions these people have? *

Diabetes: 6 people, 19.35%
Type 2 Diabetes: 5 people, 16.13%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 16.13%
Bacterial Infection: 5 people, 16.13%
Constipation: 5 people, 16.13%
Depression: 5 people, 16.13%
Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 16.13%
High Blood Pressure: 5 people, 16.13%
Pain In Extremity: 5 people, 16.13%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 16.13%

* Approximation only. Some reports may have incomplete information.

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