Morphine and Depo-estradiol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Morphine (morphine sulfate) and Depo-estradiol (estradiol cypionate). Common drug interactions include pyrexia among females and abnormal dreams among males.
The phase IV clinical study analyzes what interactions people have when they take Morphine and Depo-estradiol. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Morphine?
Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.
What is Depo-estradiol?
Depo-estradiol has active ingredients of estradiol cypionate. It is often used in birth control. eHealthMe is studying from 724 Depo-estradiol users. Check the latest studies of Depo-estradiol.
17 people who take Morphine and Depo-estradiol together, and have interactions are studied.

What are the common drug interactions of Morphine and Depo-Estradiol, by gender? *:
female:
- Pyrexia (fever)
- Retinal degeneration (death of the cells of the retina)
- Retinopathy hypertensive (acute damage to the retina of the eye due to high blood pressure)
- Surgery
- Thyroid neoplasm (tumour of thyroid)
- Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
- Headache (pain in head)
- Bladder spasm
- Increased appetite
- Intervertebral disc degeneration (spinal disc degeneration)
male:
- Abnormal dreams
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Iron deficiency
- Malignant neoplasm progression (cancer tumour came back)
- Mobility decreased (ability to move is reduced)
- Night sweats (sweating in night)
- Oesophageal cancer metastatic (cancer of oesophagues spreads to other part)
- Pain in extremity
- Poor quality sleep
- Sleep paralysis (waking up and unable to move or speak)
What are the common drug interactions of Morphine and Depo-Estradiol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal discomfort
- Cataract (clouding of the lens inside the eye)
- Ocular hypertension (intraocular pressure higher than normal)
- Retinal degeneration (death of the cells of the retina)
- Retinopathy hypertensive (acute damage to the retina of the eye due to high blood pressure)
50-59:
- Bladder spasm
- Increased appetite
- Intervertebral disc protrusion (spinal disc protrusion)
- Night sweats (sweating in night)
- Pain in extremity
- Poor quality sleep
- Somnambulism (sleep walking)
- Tooth abscess (pus formation in tooth)
- Weight increased
- Abnormal dreams
60+:
- Abdominal pain
- Arthralgia (joint pain)
- Hypokalaemia (low potassium)
- Intervertebral disc degeneration (spinal disc degeneration)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Oedema (fluid collection in tissue)
- Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Road traffic accident
What are the existing conditions these people have? *
- Back Pain: 6 people, 35.29%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 29.41%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 29.41%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 29.41%
- Depression: 4 people, 23.53%
- Stress And Anxiety: 3 people, 17.65%
- High Blood Pressure: 3 people, 17.65%
- Hypokalemia (low potassium): 2 people, 11.76%
- Indigestion: 2 people, 11.76%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Morphine and Depo-estradiol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Morphine (182,913 reports)
- Depo-estradiol (724 reports)
Browse all drug interactions of Morphine and Depo-estradiol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Morphine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Depo-estradiol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Morphine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Depo-estradiol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on morphine sulfate and estradiol cypionate (the active ingredients of Morphine and Depo-estradiol, respectively), and Morphine and Depo-estradiol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Wakix cause Urticaria? - a second ago
- Drug interactions of Amoxil and Erythromycin - 4 seconds ago
- Could Tymlos cause Feeling Jittery? - 16 seconds ago
- Could Febuxostat cause Confusion? - 21 seconds ago
- Could Ibu cause Fracture Delayed Union? - 25 seconds ago
- Drug interactions of Sonata and Lioresal - 33 seconds ago
- Drug interactions of Inositol and Pantoprazole - 34 seconds ago
- Drug interactions of Q10 and Robitussin - 34 seconds ago
- Drug interactions of Promethazine and Tarceva - 40 seconds ago
- Could Mirena cause Restlessness Aggravated? - 41 seconds ago