Motrin ib and Dexilant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Motrin ib (ibuprofen) and Dexilant (dexlansoprazole). Common drug interactions include skin ulcer among females and hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Motrin ib and Dexilant. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Motrin ib?

Motrin ib has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 3,772 Motrin ib users. Check the latest studies of Motrin ib.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

On Jul, 19, 2026

34 people who take Motrin ib and Dexilant together, and have interactions are studied.

Motrin ib and Dexilant drug interactions.

What are the common drug interactions of Motrin Ib and Dexilant, by gender? *:

female:

Skin ulcer
Synovitis (inflammation of the synovial membrane)
Tendonitis (a condition that causes pain and swelling of tendons)
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
Therapeutic response decreased (less preventive response)
Tongue disorder (disease of tongue)
Vulvovaginal dryness
Weight increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cough

male:

Hypersensitivity
Cough
C-reactive protein increased
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)
Enthesopathy (disorder of entheses (bone attachments))
Erythema (redness of the skin)
General physical health deterioration (weak health status)
Hepatic enzyme increased

What are the common drug interactions of Motrin Ib and Dexilant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Diarrhoea
Dry skin
Emotional distress
General physical health deterioration (weak health status)
Injury
Local swelling (swelling at the site of some application of substance or injury)
Productive cough
Rash

30-39:

n/a

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
C-reactive protein increased
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)
Enthesopathy (disorder of entheses (bone attachments))
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)

50-59:

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Alanine aminotransferase increased
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Aspartate aminotransferase increased
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood parathyroid hormone decreased
C-reactive protein increased
Drug hypersensitivity
Drug ineffective

60+:

Allergic sinusitis
Asthenia (weakness)
Respiratory rate decreased (less breathing rate/min)
Blood pressure decreased
Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis)
Dizziness
Hypertension (high blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Multiple allergies (allergy to multiple agents)
Sinusitis (inflammation of sinus)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 38.24%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 14.71%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 11.76%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 11.76%
Multiple Myeloma (cancer of the plasma cells): 3 people, 8.82%
Immunodeficiency Common Variable: 3 people, 8.82%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 8.82%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 8.82%
Hypersensitivity: 2 people, 5.88%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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