Movicol and Modafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Movicol (polyethylene glycol 3350) and Modafinil (modafinil). Common drug interactions include asthenia among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Movicol and Modafinil. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Movicol?

Movicol has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 14,249 Movicol users. Check the latest studies of Movicol.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 20,805 Modafinil users. Check the latest studies of Modafinil.



On Jul, 10, 2026

11 people who take Movicol and Modafinil together, and have interactions are studied.

Movicol and Modafinil drug interactions.

What are the common drug interactions of Movicol and Modafinil, by gender? *:

female:

  1. Asthenia (weakness)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Nausea (feeling of having an urge to vomit)
  4. Throat irritation
  5. Vertigo
  6. Vomiting
  7. Ankyloglossia acquired (extensive adhesion of the tongue to the palate, associated with deformities of the hands and feet)
  8. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)

male:

  1. Death
  2. Femur fracture

What are the common drug interactions of Movicol and Modafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Femur fracture

20-29:

n/a

30-39:

  1. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)

40-49:

n/a

50-59:

  1. Asthenia (weakness)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Nausea (feeling of having an urge to vomit)
  4. Throat irritation
  5. Vertigo
  6. Vomiting
  7. Ankyloglossia acquired (extensive adhesion of the tongue to the palate, associated with deformities of the hands and feet)

60+:

n/a

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 72.73%
  2. High Blood Cholesterol: 7 people, 63.64%
  3. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 7 people, 63.64%
  4. Menopause (end of monthly cycles in women): 7 people, 63.64%
  5. Sleep Disorder: 1 person, 9.09%
  6. Insomnia (sleeplessness): 1 person, 9.09%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%
  8. Fatigue (feeling of tiredness): 1 person, 9.09%
  9. Fever: 1 person, 9.09%
  10. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Movicol and Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Movicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Movicol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Modafinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and modafinil (the active ingredients of Movicol and Modafinil, respectively), and Movicol and Modafinil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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