Multivitamin and Lonsurf drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Lonsurf (tipiracil hydrochloride; trifluridine). Common drug interactions include rash erythematous among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Multivitamin and Lonsurf. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.
What is Multivitamin?
Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.
What is Lonsurf?
Lonsurf has active ingredients of tipiracil hydrochloride; trifluridine. eHealthMe is studying from 10,077 Lonsurf users. Check the latest studies of Lonsurf.
57 people who take Multivitamin and Lonsurf together, and have interactions are studied.

What are the common drug interactions of Multivitamin and Lonsurf, by gender? *:
female:
- Rash erythematous (redness of the skin)
- Red blood cell count decreased
- Renal disorder (kidney disease)
- Renal mass (mass in kidney)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Thrombosis (formation of a blood clot inside a blood vessel)
- Ureteric stenosis (abnormal narrowing or contraction of a duct or canal)
- Urinary bladder haemorrhage (urinary bladder bleeding)
- Vaginal discharge
- White blood cell count decreased
male:
- Death
- Nausea (feeling of having an urge to vomit)
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Platelet count decreased
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Adverse event
- Asthenia (weakness)
- Bladder disorder
What are the common drug interactions of Multivitamin and Lonsurf, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Blood potassium decreased
- Dehydration (dryness resulting from the removal of water)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Urinary bladder haemorrhage (urinary bladder bleeding)
- Urinary tract infection
- Vomiting
50-59:
- Death
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Stomatitis (inflammation of mucous membrane of mouth)
- Weight decreased
- Dyspnoea (difficult or laboured respiration)
- Haemoglobin decreased
60+:
- Fatigue (feeling of tiredness)
- Death
- Red blood cell count decreased
- Urinary tract infection
- Disease progression
- Platelet count decreased
- Vomiting
- Kidney infection
- Neuropathy peripheral (surface nerve damage)
- Abdominal discomfort
What are the existing conditions these people have? *
- Colon Cancer: 39 people, 68.42%
- Rectal Cancer (cancer of rectum): 8 people, 14.04%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 5 people, 8.77%
- Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Multivitamin and Lonsurf?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Multivitamin (83,597 reports)
- Lonsurf (10,077 reports)
Browse all drug interactions of Multivitamin and Lonsurf:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Multivitamin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lonsurf:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Multivitamin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lonsurf and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and tipiracil hydrochloride; trifluridine (the active ingredients of Multivitamin and Lonsurf, respectively), and Multivitamin and Lonsurf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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