Multivitamin and Sotret drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Sotret (isotretinoin). Common drug interactions include blood cholesterol increased among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Multivitamin and Sotret. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Multivitamin?

Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.

What is Sotret?

Sotret has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,023 Sotret users. Check the latest studies of Sotret.



On Jul, 11, 2026

13 people who take Multivitamin and Sotret together, and have interactions are studied.

Multivitamin and Sotret drug interactions.

What are the common drug interactions of Multivitamin and Sotret, by gender? *:

female:

  1. Blood cholesterol increased
  2. Blood triglycerides increased
  3. Diarrhoea
  4. Headache (pain in head)
  5. Lip dry
  6. Loss of consciousness
  7. Adjustment disorder
  8. Blood sodium decreased
  9. Crying
  10. Fluid retention (an abnormal accumulation of fluid in the blood)

male:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Cystic fibrosis (disease of the secretary glands)

What are the common drug interactions of Multivitamin and Sotret, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Hyperbilirubinaemia (excess of bilirubin in the blood)
  4. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  5. Hypokalaemia (low potassium)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Pain
  8. Pruritus (severe itching of the skin)
  9. Pyrexia (fever)
  10. Weight increased

10-19:

  1. Adjustment disorder
  2. Arthralgia (joint pain)
  3. Crying
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Mood altered (changes in mood)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Personality change
  9. Quality of life decreased
  10. Social avoidant behaviour (avoiding social connection a personality disorder)

20-29:

  1. Abdominal pain
  2. Alanine aminotransferase increased
  3. Loss of libido (loss of sexual urge)
  4. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
  5. Arthralgia (joint pain)
  6. Aspartate aminotransferase increased
  7. Back pain
  8. Diarrhoea
  9. Dizziness
  10. Headache (pain in head)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Neuroblastoma (a cancer that forms in your nerve tissue): 2 people, 15.38%
  2. Pain: 1 person, 7.69%
  3. Nausea (feeling of having an urge to vomit): 1 person, 7.69%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%
  5. Fever: 1 person, 7.69%
  6. Cystic Fibrosis (disease of the secretary glands): 1 person, 7.69%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%
  8. Constipation: 1 person, 7.69%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 7.69%
  10. Asthma: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Multivitamin and Sotret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Multivitamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sotret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multivitamin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sotret and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and isotretinoin (the active ingredients of Multivitamin and Sotret, respectively), and Multivitamin and Sotret (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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