Naproxen sodium and Centrum silver drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen sodium (naproxen sodium) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include bleeding varicose vein among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen sodium and Centrum silver. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen sodium?

Naproxen sodium has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 11,252 Naproxen sodium users. Check the latest studies of Naproxen sodium.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

23 people who take Naproxen sodium and Centrum silver together, and have interactions are studied.

Naproxen sodium and Centrum silver drug interactions.

What are the common drug interactions of Naproxen Sodium and Centrum Silver, by gender? *:

female:

Bleeding varicose vein
Hypotension (abnormally low blood pressure)
Arthralgia (joint pain)
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Dizziness
Drug ineffective
Hypersensitivity
Injection site erythema (redness at injection site)
Injection site pain

male:

Diarrhoea
Constipation
Blood glucose decreased
Blood glucose fluctuation
Chest pain
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Disease progression
Drug ineffective
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Naproxen Sodium and Centrum Silver, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chest pain
Constipation
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Dizziness
Haematochezia (passage of stools containing blood)
Hypersensitivity
Injection site erythema (redness at injection site)
Injection site pain
Muscle disorder (muscle disease)

60+:

Diarrhoea
Hypotension (abnormally low blood pressure)
Balance disorder
Blood glucose decreased
Blood glucose fluctuation
Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Disease progression
Drug ineffective

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 21.74%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 17.39%
Osteoporosis (bones weak and more likely to break): 3 people, 13.04%
High Blood Pressure: 3 people, 13.04%
High Blood Cholesterol: 3 people, 13.04%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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