Naproxen and Aldara drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Aldara (imiquimod). Common drug interactions include keloid scar among females and erysipelas among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Aldara. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Aldara?

Aldara has active ingredients of imiquimod. It is often used in genital warts. eHealthMe is studying from 2,554 Aldara users. Check the latest studies of Aldara.

On Jul, 17, 2026

21 people who take Naproxen and Aldara together, and have interactions are studied.

What are the common drug interactions of Naproxen and Aldara, by gender? *:

female:

Keloid scar (overgrown scars left from skin injuries)
Laryngocele (a congenital anomalous air sac communicating with the cavity of the larynx)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Maternal exposure during pregnancy (use of substance during pregnancy)
Mediastinal cyst (fluid filled sac in an undelineated group of structures in the thorax, surrounded by loose connective tissue)
Mediastinal mass (mass in the part of the chest that separates the lungs)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

male:

Erysipelas (bacterial skin infection)
Anaemia postoperative
Influenza
Intervertebral disc protrusion (spinal disc protrusion)
Limb asymmetry (consistent task discrepancy between the two lower limbs)
Limb deformity (functional disability of leg)
Lower limb fracture
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)

What are the common drug interactions of Naproxen and Aldara, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Fatigue (feeling of tiredness)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pulmonary congestion (congestion in the lungs)
Upper respiratory tract infection

20-29:

n/a

30-39:

Chest pain
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Diaphragmatic disorder
Hyperacusis (disorder in loudness perception)
Influenza like illness
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Post viral fatigue syndrome
Sleep disorder

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Influenza
Joint dislocation (a joint position is changed from normal position)
Joint range of motion decreased (disease of joint movement)
Joint swelling
Malaise (a feeling of general discomfort or uneasiness)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

50-59:

Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
Rash
Anaphylactic reaction (serious allergic reaction)
Body temperature increased
Cardiac hypertrophy (thickening of the heart muscle)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug level increased
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)

60+:

Anaemia postoperative
Fall
Haematuria (presence of blood in urine)
Intervertebral disc protrusion (spinal disc protrusion)
Pneumonia
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Renal failure (kidney dysfunction)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Femur fracture
Fracture displacement

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.52%
Pleurisy (inflammation of the pleurae, which causes pain when breathing): 2 people, 9.52%
Depression: 2 people, 9.52%
Birth Control: 2 people, 9.52%
Actinic Keratosis (skin disease due to sun exposure): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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