Naproxen and Anusol hc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Anusol hc (hydrocortisone). Common drug interactions include sciatica among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Anusol hc. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Anusol hc?

Anusol hc has active ingredients of hydrocortisone. It is often used in hemorrhoids. eHealthMe is studying from 679 Anusol hc users. Check the latest studies of Anusol hc.



On Jul, 27, 2026

15 people who take Naproxen and Anusol hc together, and have interactions are studied.

Naproxen and Anusol hc drug interactions.

What are the common drug interactions of Naproxen and Anusol Hc, by gender? *:

female:

  1. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  2. Skin discolouration (change of skin colour)
  3. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  4. Vaginal haemorrhage (vaginal bleeding)
  5. Abdominal distension
  6. Abdominal pain
  7. Abdominal pain lower
  8. Blood in stool
  9. Bradycardia (abnormally slow heart action)
  10. Confusional state

male:

  1. Bradycardia (abnormally slow heart action)
  2. Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Naproxen and Anusol Hc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Confusional state
  2. Loss of consciousness

40-49:

  1. Neuropathy peripheral (surface nerve damage)
  2. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  3. Skin discolouration (change of skin colour)
  4. Vaginal haemorrhage (vaginal bleeding)
  5. Abdominal distension
  6. Abdominal pain
  7. Abdominal pain lower
  8. Blood in stool
  9. Constipation
  10. Depression

50-59:

n/a

60+:

  1. Bradycardia (abnormally slow heart action)
  2. Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

  1. Bone Disorder: 10 people, 66.67%
  2. Acetabulum Fracture (socket of the hip joint- fracture): 8 people, 53.33%
  3. Breast Cancer Metastatic: 7 people, 46.67%
  4. Vulvovaginal Candidiasis (vulvovaginal infection by fungi): 1 person, 6.67%
  5. Urinary Tract Infection: 1 person, 6.67%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
  7. Neck Pain: 1 person, 6.67%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%
  9. Muscle Spasms (muscle contraction): 1 person, 6.67%
  10. Irritable Bowel Syndrome: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and Anusol hc?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naproxen and Anusol hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Anusol hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naproxen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anusol hc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen and hydrocortisone (the active ingredients of Naproxen and Anusol hc, respectively), and Naproxen and Anusol hc (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: