Naproxen and Clexane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Clexane (enoxaparin sodium). Common drug interactions include haematemesis among females and intestinal perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Clexane. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Clexane?

Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.

On Jul, 15, 2026

32 people who take Naproxen and Clexane together, and have interactions are studied.

What are the common drug interactions of Naproxen and Clexane, by gender? *:

female:

Haematemesis (vomiting of blood)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Infection
Infusion related reaction
Asthma
Cardiac failure
Cardiac failure congestive
Respiratory tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Intestinal perforation (complete penetration of the wall of the intestine)
Muscular weakness (muscle weakness)
Agitation (state of anxiety or nervous excitement)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)

What are the common drug interactions of Naproxen and Clexane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Neutropenia (an abnormally low number of neutrophils)
Infection
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myalgia (muscle pain)
Tendon injury
Tendon rupture (tear of tendon)
Oesophageal haemorrhage (bleeding from oesophagus)
Oesophagitis (inflammation of oesophagus)

60+:

Abdominal pain upper
Flatulence (flatus expelled through the anus)
Cardiac failure congestive
Respiratory tract infection
Pyrexia (fever)
Agitation (state of anxiety or nervous excitement)
Blood bilirubin increased
Blood fibrinogen increased
Blood glucose increased
Confusional state

What are the existing conditions these people have? *

Mucosal Inflammation (infection of mucous membrane): 10 people, 31.25%
Nausea (feeling of having an urge to vomit): 9 people, 28.12%
Anaemia (lack of blood): 7 people, 21.88%
Mouth Ulcers: 6 people, 18.75%
Hypotension (abnormally low blood pressure): 6 people, 18.75%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 5 people, 15.62%
Menopausal Symptoms: 5 people, 15.62%
Joint Pain: 5 people, 15.62%
Infection: 5 people, 15.62%
Urinary Tract Infection: 5 people, 15.62%

* Approximation only. Some reports may have incomplete information.

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