Naproxen and Cyklokapron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Cyklokapron (tranexamic acid). Common drug interactions include arthralgia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Cyklokapron. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.

What is Cyklokapron?

Cyklokapron has active ingredients of tranexamic acid. It is often used in heavy or prolong menstrual bleeding. eHealthMe is studying from 835 Cyklokapron users. Check the latest studies of Cyklokapron.



On Aug, 03, 2026

16 people who take Naproxen and Cyklokapron together, and have interactions are studied.

Naproxen and Cyklokapron drug interactions.

What are the common drug interactions of Naproxen and Cyklokapron, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Blood pressure fluctuation
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Muscle spasms (muscle contraction)
  5. Infusion related reaction
  6. Uterine disorder
  7. Onychoclasis (breaking of the nails)
  8. Weight decreased
  9. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  10. Blood iron decreased

male:

  1. Chronic kidney disease
  2. Osteonecrosis (death of bone)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Blood creatinine increased
  6. Bone density decreased
  7. Emotional distress
  8. Hip arthroplasty
  9. Renal impairment (severely reduced kidney function)
  10. Tooth loss

What are the common drug interactions of Naproxen and Cyklokapron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthralgia (joint pain)
  2. Blood pressure fluctuation
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Muscle spasms (muscle contraction)
  5. Onychoclasis (breaking of the nails)
  6. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  7. Blood iron decreased
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Deformity (disfigurement)
  10. Dizziness

40-49:

  1. Chronic kidney disease
  2. Osteonecrosis (death of bone)
  3. Dental discomfort
  4. Fall
  5. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  6. Hereditary angioedema (recurrent episodes of severe swelling)
  7. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

50-59:

  1. Anaemia (lack of blood)
  2. Arthralgia (joint pain)
  3. Drug intolerance (drug sensitivity)
  4. Cough
  5. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  6. Diarrhoea
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. General physical condition
  9. Influenza
  10. Malaise (a feeling of general discomfort or uneasiness)

60+:

n/a

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 75.00%
  2. High Blood Pressure: 8 people, 50.00%
  3. Joint Pain: 4 people, 25.00%
  4. Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 18.75%
  5. Hiv Infection: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and Cyklokapron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naproxen and Cyklokapron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyklokapron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naproxen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyklokapron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen and tranexamic acid (the active ingredients of Naproxen and Cyklokapron, respectively), and Naproxen and Cyklokapron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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