Naproxen and Monopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Monopril (fosinopril sodium). Common drug interactions include eczema among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Monopril. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,034 Naproxen users. Check the latest studies of Naproxen.

What is Monopril?

Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

54 people who take Naproxen and Monopril together, and have interactions are studied.

Naproxen and Monopril drug interactions.

What are the common drug interactions of Naproxen and Monopril, by gender? *:

female:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fall
Gait disturbance
Haematochezia (passage of stools containing blood)
Hypoaesthesia (reduced sense of touch or sensation)
Joint sprain (an injury to joint surrounding flexible fibres)
Muscular weakness (muscle weakness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Neck mass (mass in neck)
Oedema (fluid collection in tissue)

male:

Chest pain
Depression
Pulmonary embolism (blockage of the main artery of the lung)
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Oedema upper limb (swelling of arm)
Phlebitis (inflammation of the walls of a vein)
Bone disorder

What are the common drug interactions of Naproxen and Monopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cholecystitis (infection of gallbladder)
Influenza like illness
Insomnia (sleeplessness)
Urinary tract infection
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)

30-39:

Drug dependence

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Abdominal pain
Type 2 diabetes mellitus
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Chest pain
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrointestinal pain
Non-cardiac chest pain

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Depression
Myalgia (muscle pain)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Urinary tract infection
Abdominal distension
Altered state of consciousness (altered state of mind)

60+:

Asthenia (weakness)
Arthralgia (joint pain)
Pyrexia (fever)
Urticaria (rash of round, red welts on the skin that itch intensely)
Chronic kidney disease
Gastric cancer (stomach cancer)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Atrioventricular block (heart block)
Blood creatinine increased

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 11 people, 20.37%
Breast Cancer: 11 people, 20.37%
Bone Pain: 11 people, 20.37%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 20.37%
Constipation: 10 people, 18.52%
Depression: 6 people, 11.11%
Nausea And Vomiting: 5 people, 9.26%
Intervertebral Disc Degeneration (spinal disc degeneration): 5 people, 9.26%
Glossitis (infection of tongue with soreness): 5 people, 9.26%
Dissociative Disorder: 5 people, 9.26%

* Approximation only. Some reports may have incomplete information.

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