Naproxen and Ocaliva drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Naproxen (naproxen) and Ocaliva (obeticholic acid). Common drug interactions include pruritus among females.
The phase IV clinical study analyzes what interactions people have when they take Naproxen and Ocaliva. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Naproxen?
Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.
What is Ocaliva?
Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.
16 people who take Naproxen and Ocaliva together, and have interactions are studied.

What are the common drug interactions of Naproxen and Ocaliva, by gender? *:
female:
- Pruritus (severe itching of the skin)
- Arthralgia (joint pain)
- Aphasia (damage to the parts of the brain that control language)
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Death
- Ill-defined disorder
- Pruritus generalised (generalized itching)
- Blood bilirubin increased
- Fractured sacrum
male:
n/a
What are the common drug interactions of Naproxen and Ocaliva, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pruritus (severe itching of the skin)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Arthralgia (joint pain)
- Blood bilirubin increased
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Death
- Ill-defined disorder
- Pruritus generalised (generalized itching)
- Fractured sacrum
- Gait disturbance
- Haematoma (collection of blood outside the blood vessels)
What are the existing conditions these people have? *
- Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 7 people, 43.75%
- High Blood Pressure: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Naproxen and Ocaliva?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Naproxen and Ocaliva:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Naproxen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ocaliva:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naproxen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ocaliva and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naproxen and obeticholic acid (the active ingredients of Naproxen and Ocaliva, respectively), and Naproxen and Ocaliva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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