Naproxen and Omacor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Omacor (omega-3acid ethyl esters). Common drug interactions include memory impairment among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Omacor. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Omacor?

Omacor has active ingredients of omega-3acid ethyl esters. It is often used in high blood cholesterol. eHealthMe is studying from 2,547 Omacor users. Check the latest studies of Omacor.



On Jul, 13, 2026

14 people who take Naproxen and Omacor together, and have interactions are studied.

Naproxen and Omacor drug interactions.

What are the common drug interactions of Naproxen and Omacor, by gender? *:

female:

  1. Memory impairment
  2. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
  5. Migraine (headache)
  6. Muscle twitching
  7. Muscular weakness (muscle weakness)
  8. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  9. Arthralgia (joint pain)
  10. Anxiety

male:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Intervertebral disc disorder (spinal disc disorder)
  4. Oedema peripheral (superficial swelling)
  5. Pain in extremity
  6. Post procedural complication
  7. Surgery
  8. Activities of daily living impaired
  9. Discomfort
  10. Inflammation

What are the common drug interactions of Naproxen and Omacor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain upper
  2. Abnormal weight gain
  3. Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
  4. Gallbladder non-functioning
  5. Nausea (feeling of having an urge to vomit)
  6. Abdominal distension

20-29:

n/a

30-39:

n/a

40-49:

  1. Hyperlipidaemia (presence of excess lipids in the blood)
  2. Hypertriglyceridaemia (excess of triglycerides in the blood)

50-59:

  1. Anxiety
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Thrombosis (formation of a blood clot inside a blood vessel)

60+:

  1. Abdominal discomfort
  2. Abdominal pain
  3. Abdominal mass (localized enlargement or swelling in the human abdomen)
  4. Affect lability (emotional incontinence)
  5. Anaemia (lack of blood)
  6. Ankle fracture
  7. Anosognosia (ignorance of the presence of disease)
  8. Anxiety
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Apathy

What are the existing conditions these people have? *

  1. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 35.71%
  2. Diabetes: 4 people, 28.57%
  3. Hypertriglyceridaemia (excess of triglycerides in the blood): 2 people, 14.29%
  4. Thyroid Diseases: 1 person, 7.14%
  5. Blood Calcium Decreased: 1 person, 7.14%
  6. Blood Pressure Abnormal: 1 person, 7.14%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
  8. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 7.14%
  9. Depression: 1 person, 7.14%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and Omacor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naproxen and Omacor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Omacor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naproxen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Omacor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen and omega-3acid ethyl esters (the active ingredients of Naproxen and Omacor, respectively), and Naproxen and Omacor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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