Naproxen and Persantine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Naproxen (naproxen) and Persantine (dipyridamole). Common drug interactions include electrocardiogram repolarisation abnormality among females and abdominal pain upper among males.
The phase IV clinical study analyzes what interactions people have when they take Naproxen and Persantine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Naproxen?
Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,033 Naproxen users. Check the latest studies of Naproxen.
What is Persantine?
Persantine has active ingredients of dipyridamole. eHealthMe is studying from 2,427 Persantine users. Check the latest studies of Persantine.
17 people who take Naproxen and Persantine together, and have interactions are studied.

What are the common drug interactions of Naproxen and Persantine, by gender? *:
female:
- Electrocardiogram repolarisation abnormality
- Electrocardiogram st-t change
- Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
- Injury
- Mitral valve incompetence (inefficient heart valve)
- Myalgia (muscle pain)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Postpartum disorder (moderate to severe depression in a woman after she has given birth)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Surgery
male:
- Abdominal pain upper
- Anuria (failure of the kidneys to produce urine)
- Chronic kidney disease
- Decreased appetite
- Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
- Depression
- Hyperphagia (an abnormal appetite for food)
- Hypersexuality
- Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
What are the common drug interactions of Naproxen and Persantine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Influenza like illness
- Insomnia (sleeplessness)
- Urinary tract infection
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Intracardiac thrombus (presence of a circumscribed mass with heart wall)
- Mass
- Multi-organ failure (multisystem organ failure)
- Presyncope
- Renal failure (kidney dysfunction)
- Sinusitis (inflammation of sinus)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Haemorrhagic anaemia (anaemia due to excessive bleeding)
- Intervertebral disc degeneration (spinal disc degeneration)
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
- Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
- Weight decreased
What are the existing conditions these people have? *
- High Blood Cholesterol: 4 people, 23.53%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
- Type 2 Diabetes: 2 people, 11.76%
- Diabetes: 2 people, 11.76%
- Peripartum Cardiomyopathy (deterioration in cardiac function presenting typically between the last month of pregnancy and up to five months postpartum): 2 people, 11.76%
- Gastric Cancer (stomach cancer): 2 people, 11.76%
- Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 11.76%
- Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 2 people, 11.76%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
- Erection Problems: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Naproxen and Persantine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Naproxen (72,033 reports)
- Persantine (2,427 reports)
Browse all drug interactions of Naproxen and Persantine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Naproxen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Persantine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naproxen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Persantine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on naproxen and dipyridamole (the active ingredients of Naproxen and Persantine, respectively), and Naproxen and Persantine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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