Naproxen and Plan b drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Plan b (levonorgestrel). Common drug interactions include menstruation irregular among females.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Plan b. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Plan b?

Plan b has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 38,623 Plan b users. Check the latest studies of Plan b.

On Jul, 13, 2026

42 people who take Naproxen and Plan b together, and have interactions are studied.

What are the common drug interactions of Naproxen and Plan B, by gender? *:

female:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Maternal exposure during pregnancy (use of substance during pregnancy)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal pain
Fatigue (feeling of tiredness)
Depression
Vomiting

male:

n/a

What are the common drug interactions of Naproxen and Plan B, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Menstruation irregular
Nausea (feeling of having an urge to vomit)
Menstruation delayed (late menstruation cycle)
Vomiting
Abdominal distension
Abdominal pain
Abdominal pain upper
Abnormal faeces (abnormal stool)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Ankle fracture

20-29:

Suicidal ideation
Suicide attempt
Thrombosis (formation of a blood clot inside a blood vessel)
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
Vomiting
Menstruation irregular
Pelvic pain
Pregnancy after post coital contraception
Aggression
Agitation (state of anxiety or nervous excitement)

30-39:

Dizziness
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Loss of consciousness
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Menstruation irregular
Drug ineffective
Maternal exposure during pregnancy (use of substance during pregnancy)
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Menstruation irregular
Osteopenia (a condition where bone mineral density is lower than normal)
Menstruation delayed (late menstruation cycle)
Multiple fractures
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Spinal fracture (fracture in one of vertebrae)
Sternal fracture
Upper limb fracture
Wrist fracture
Dizziness

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Headache (pain in head): 6 people, 14.29%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 11.90%
Migraine (headache): 4 people, 9.52%
Back Pain: 4 people, 9.52%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.14%
Gastric Disorder (disease of stomach): 3 people, 7.14%
Dysmenorrhea (painful menstruation): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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