Naratriptan and Clonazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naratriptan (naratriptan) and Clonazepam (clonazepam). Common drug interactions include aphasia among females and bone loss among males.

The phase IV clinical study analyzes what interactions people have when they take Naratriptan and Clonazepam. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Naratriptan?

Naratriptan has active ingredients of naratriptan. It is often used in migraine. eHealthMe is studying from 1,481 Naratriptan users. Check the latest studies of Naratriptan.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,272 Clonazepam users. Check the latest studies of Clonazepam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

65 people who take Naratriptan and Clonazepam together, and have interactions are studied.

Naratriptan and Clonazepam drug interactions.

What are the common drug interactions of Naratriptan and Clonazepam, by gender? *:

female:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Arthralgia (joint pain)
  3. Depression
  4. Suicidal ideation
  5. Dry eye (lack of adequate tears)
  6. Drug ineffective
  7. Chronic kidney disease
  8. Dizziness
  9. Drug dependence
  10. Drug hypersensitivity

male:

  1. Bone loss
  2. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Dyspnoea (difficult or laboured respiration)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Insomnia (sleeplessness)
  7. Irritability
  8. Muscular weakness (muscle weakness)
  9. Overdose
  10. Pathogen resistance

What are the common drug interactions of Naratriptan and Clonazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Nausea (feeling of having an urge to vomit)
  2. Abdominal pain upper
  3. Arthralgia (joint pain)
  4. Dehydration (dryness resulting from the removal of water)
  5. Diarrhoea
  6. Dizziness
  7. Hallucination (an experience involving the perception of something not present)
  8. Headache (pain in head)
  9. Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
  10. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

20-29:

  1. Dry eye (lack of adequate tears)
  2. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
  3. Dental caries
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Tooth erosion (dissolving teeth)

30-39:

  1. Breakthrough pain
  2. Decreased appetite
  3. Dysgeusia (disorder of the sense of taste)
  4. Facial pain
  5. Hyperhidrosis (abnormally increased sweating)
  6. Hypersensitivity
  7. Mobility decreased (ability to move is reduced)
  8. Muscle spasms (muscle contraction)
  9. Neck pain
  10. Pain in extremity

40-49:

  1. Lip swelling
  2. Neuralgia (pain in one or more nerves)
  3. Overdose
  4. Pathogen resistance
  5. Pyrexia (fever)
  6. Somatoform disorder (a mental disorder characterized by symptoms that suggest physical illness or injury)
  7. Syncope (loss of consciousness with an inability to maintain postural tone)
  8. Bone loss
  9. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  10. Deafness bilateral

50-59:

  1. Depression
  2. Agitation (state of anxiety or nervous excitement)
  3. Mood swings (an extreme or rapid change in mood)
  4. Sleep disorder
  5. Suicidal ideation
  6. Acute interstitial pneumonitis (acute revere lung disease)
  7. Acute respiratory failure
  8. Back pain
  9. Insomnia (sleeplessness)
  10. Kidney infection

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Abdominal discomfort
  5. Drug ineffective
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Dyspnoea (difficult or laboured respiration)
  8. Headache (pain in head)
  9. Muscular weakness (muscle weakness)
  10. Visual acuity reduced (reduced clearness of vision)

What are the existing conditions these people have? *

  1. Pain: 17 people, 26.15%
  2. Nausea (feeling of having an urge to vomit): 16 people, 24.62%
  3. Depression: 14 people, 21.54%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 15.38%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 15.38%
  6. Insomnia (sleeplessness): 8 people, 12.31%
  7. Headache (pain in head): 7 people, 10.77%
  8. Asthma: 6 people, 9.23%
  9. High Blood Cholesterol: 6 people, 9.23%
  10. High Blood Pressure: 5 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Naratriptan and Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naratriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naratriptan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on naratriptan and clonazepam (the active ingredients of Naratriptan and Clonazepam, respectively), and Naratriptan and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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