Nesina and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nesina (alogliptin benzoate) and Avapro (irbesartan). Common drug interactions include pemphigoid among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Nesina and Avapro. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Nesina?

Nesina has active ingredients of alogliptin benzoate. eHealthMe is studying from 2,297 Nesina users. Check the latest studies of Nesina.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.



On Jul, 29, 2026

14 people who take Nesina and Avapro together, and have interactions are studied.

Nesina and Avapro drug interactions.

What are the common drug interactions of Nesina and Avapro, by gender? *:

female:

  1. Pemphigoid (tense blisters on the skin)
  2. Glycosylated haemoglobin increased
  3. Urine ketone body present
  4. Acquired haemophilia (bleeding disorder disease)
  5. Cardiac failure acute
  6. Cerebral infarction (less blood supply to brain resulting tissue damage)
  7. Hyperglycaemia (high blood sugar)
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

male:

  1. Interstitial lung disease
  2. Pancreatitis acute (sudden inflammation of pancreas)
  3. Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Cardiac failure
  6. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  7. Decreased appetite
  8. Disease complication
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

What are the common drug interactions of Nesina and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Interstitial lung disease

60+:

  1. Pemphigoid (tense blisters on the skin)
  2. Glycosylated haemoglobin increased
  3. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  4. Decreased appetite
  5. Disease complication
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  8. Hyperglycaemia (high blood sugar)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 9 people, 64.29%
  2. Diabetes: 4 people, 28.57%
  3. Dyslipidaemia (abnormal amount of lipids): 2 people, 14.29%
  4. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 14.29%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 7.14%
  7. Haemostasis (stopping of bleeding): 1 person, 7.14%
  8. Gastritis - Chronic (long lasting inflammation of stomach): 1 person, 7.14%
  9. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 7.14%
  10. Diabetic Nephropathy (diabetic kidney disease): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Nesina and Avapro?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nesina and Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nesina:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nesina and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on alogliptin benzoate and irbesartan (the active ingredients of Nesina and Avapro, respectively), and Nesina and Avapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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