Ibuprofen and Epididymitis - a phase IV clinical study of FDA data

Summary:

Epididymitis is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are 60+ old, have been taking the drug for < 1 month also take Calcium, and have Depression.

The phase IV clinical study analyzes which people have Epididymitis when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Epididymitis?

Epididymitis (pain in the scrotum or testicle) is found to be associated with 256 drugs and 397 conditions by eHealthMe. Check the latest studies of Epididymitis.



On Jul, 29, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 54 people (0.02%) have Epididymitis.

Could Ibuprofen cause Epididymitis?

Among these 54 people:

How long have people been on Ibuprofen when they have Epididymitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Epididymitis when taking Ibuprofen? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.76 %
  • 20-29: 2.38 %
  • 30-39: 30.95 %
  • 40-49: 2.38 %
  • 50-59: 21.43 %
  • 60+: 38.1 %

What are other drugs people take besides Ibuprofen? *

  1. Paracetamol: 11 people, 20.37%
  2. Calcium: 11 people, 20.37%
  3. Levaquin: 6 people, 11.11%
  4. Tamsulosin: 6 people, 11.11%
  5. Flomax: 6 people, 11.11%
  6. Motrin: 5 people, 9.26%
  7. Digoxin: 5 people, 9.26%
  8. Cosentyx: 4 people, 7.41%
  9. Celexa: 4 people, 7.41%
  10. Aspirin: 4 people, 7.41%

What are other side effects people have besides Epididymitis? *

  1. Urinary Tract Infection: 18 people, 33.33%
  2. Drug Ineffective: 15 people, 27.78%
  3. Hydrocele: 12 people, 22.22%
  4. Sinusitis (inflammation of sinus): 8 people, 14.81%
  5. Fatigue (feeling of tiredness): 5 people, 9.26%
  6. Prostatitis (inflammation of the prostate gland): 5 people, 9.26%
  7. Sinus Congestion (blockage of sinus): 5 people, 9.26%
  8. Enlarged Prostate: 4 people, 7.41%
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 7.41%
  10. Nosebleed (bleeding from nose): 4 people, 7.41%

What are the existing conditions these people have? *

  1. Depression: 18 people, 33.33%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 24.07%
  3. Affect Lability (emotional incontinence): 3 people, 5.56%
  4. Enlarged Prostate: 3 people, 5.56%
  5. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 5.56%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 3.70%
  7. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 3.70%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 3.70%
  9. Hair Loss: 2 people, 3.70%
  10. High Blood Pressure: 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Epididymitis?

- Check whether Epididymitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Epididymitis treatments and more:

How severe was Epididymitis and when was it recovered:

Expand to all the drugs that have ingredients of ibuprofen:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epididymitis:

Browse all the conditions that are associated with Epididymitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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