Neupogen and Afinitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupogen (filgrastim) and Afinitor (everolimus). Common drug interactions include ear pain among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Neupogen and Afinitor. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

42 people who take Neupogen and Afinitor together, and have interactions are studied.

Neupogen and Afinitor drug interactions.

What are the common drug interactions of Neupogen and Afinitor, by gender? *:

female:

Ear pain
Emotional distress
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
General physical health deterioration (weak health status)
Hepatic mass
Lymphangiosis carcinomatosa (inflammation of the lymph vessels can lead to cancer)
Melaena (the passage of black, tarry stools)
Metastases to lung (cancer spreads to lung)
Metastases to pleura (cancer spreads to pleura)
Nervousness

male:

Arthralgia (joint pain)
Constipation
Pain in extremity
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinus headache (headache caused by sinus infections)
Soft tissue infection
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
Thrombocytopenia (decrease of platelets in blood)
Vision blurred
Dizziness

What are the common drug interactions of Neupogen and Afinitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death

40-49:

General physical health deterioration (weak health status)
Arthralgia (joint pain)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Device related infection
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hospitalisation
Infection

50-59:

Dyspnoea (difficult or laboured respiration)
Infection
Iron deficiency anaemia
Oesophagitis (inflammation of oesophagus)
Osteonecrosis of jaw (death of bone of jaw)
Radiation pneumonitis (inflammation of lung due to radiation)
Tooth infection
Toothache (tooth pain)
Wheezing (a high-pitched whistling sound made while you breath)
Abdominal discomfort

60+:

Malignant neoplasm progression (cancer tumour came back)
Lumbar vertebral fracture
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Diarrhoea
Feeling cold
Flatulence (flatus expelled through the anus)
Frequent bowel movements
Heart rate decreased
Inflammation

What are the existing conditions these people have? *

Neuroendocrine Tumor: 16 people, 38.10%
Carcinoid Tumor: 14 people, 33.33%
Breast Cancer: 6 people, 14.29%
High Blood Pressure: 5 people, 11.90%
Depression: 4 people, 9.52%
Radiation Pneumonitis (inflammation of lung due to radiation): 3 people, 7.14%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 7.14%
Metastases To Lymph Nodes (cancer spreads to lymph node): 3 people, 7.14%
Iron Deficiency Anaemia: 3 people, 7.14%
Device Related Infection: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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