Neupogen and Zopiclone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Neupogen (filgrastim) and Zopiclone (eszopiclone). Common drug interactions include pain in extremity among females and herpes simplex among males.

The phase IV clinical study analyzes what interactions people have when they take Neupogen and Zopiclone. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,331 Zopiclone users. Check the latest studies of Zopiclone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

92 people who take Neupogen and Zopiclone together, and have interactions are studied.

Neupogen and Zopiclone drug interactions.

What are the common drug interactions of Neupogen and Zopiclone, by gender? *:

female:

Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Psoriasis (immune-mediated disease that affects the skin)
Vaginal haemorrhage (vaginal bleeding)
Vomiting
Cellulitis (infection under the skin)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Adult t-cell lymphoma/leukaemia (cancer of the immune system's own t-cells)

male:

Herpes simplex (herpes simplex is a common viral infection)
Drug intolerance (drug sensitivity)
Systolic dysfunction (impaired ventricular contraction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaemia (lack of blood)
Angiosarcoma (cancer of endothelial-type cells that line vessel walls)
Bedridden
Central line infection (infection by central line in icu)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Colitis (inflammation of colon)

What are the common drug interactions of Neupogen and Zopiclone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Congestive cardiomyopathy (weakening of heart muscle)
Diastolic dysfunction
Dyspnoea exertional (breathlessness or shortness of breath)
Systolic dysfunction (impaired ventricular contraction)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Abdominal pain
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Colitis (inflammation of colon)
Febrile neutropenia (fever with reduced white blood cells)
Heart rate increased
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Respiratory failure (inadequate gas exchange by the respiratory system)

40-49:

Vomiting
Central line infection (infection by central line in icu)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Dysphagia (a condition in which swallowing is difficult or painful)
Enterococcal infection
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
Lymphangitis (inflammation of the lymph channel)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pyrexia (fever)
Rash scarlatiniform (rash 3-5mm size)

50-59:

Chorioretinitis (an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye)
Decreased eye contact
Eye allergy
Infection
Influenza like illness
Joint swelling
Oropharyngeal pain
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rash
Rash erythematous (redness of the skin)

60+:

Herpes simplex (herpes simplex is a common viral infection)
Drug intolerance (drug sensitivity)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Cushingoid (obesity and weakening of the muscles)
Decreased appetite
Diffuse large b-cell lymphoma stage iv (cancer of b cells, a type of white blood cell-stage iv)
Drug ineffective
Epistaxis (bleed from the nose)
Hot flush (sudden feelings of heat)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 30 people, 32.61%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 26 people, 28.26%
Indigestion: 24 people, 26.09%
Conjunctivitis (pink eye): 23 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 16 people, 17.39%
White Blood Cell Count Decreased: 10 people, 10.87%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 7 people, 7.61%
Pain: 6 people, 6.52%
High Blood Pressure: 6 people, 6.52%
Cough: 6 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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