Nexium and Amphetamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Amphetamine (amphetamine). Common drug interactions include nephrogenic anaemia among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Nexium and Amphetamine. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
What is Amphetamine?
Amphetamine has active ingredients of amphetamine. eHealthMe is studying from 980 Amphetamine users. Check the latest studies of Amphetamine.
12 people who take Nexium and Amphetamine together, and have interactions are studied.

What are the common drug interactions of Nexium and Amphetamine, by gender? *:
female:
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal tubular necrosis (death of kidney tubules)
- Cardiac arrest
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Death
- Impaired gastric emptying
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal pain
male:
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Chronic kidney disease
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the common drug interactions of Nexium and Amphetamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anal abscess
- Cellulitis (infection under the skin)
- Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
- Gangrene (body tissue dies)
- Genital abscess (build up of pus in genital)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Perineal abscess
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urinary tract infection
- Vulval abscess
50-59:
- Chronic kidney disease
- Renal injury (kidney injury)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Renal tubular necrosis (death of kidney tubules)
- Impaired gastric emptying
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal pain
60+:
- Chronic kidney disease
- Cardiac arrest
- Cardiac failure congestive
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Death
- Renal failure (kidney dysfunction)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 58.33%
- Depression: 6 people, 50.00%
- High Blood Cholesterol: 5 people, 41.67%
- Pain: 4 people, 33.33%
- Indigestion: 4 people, 33.33%
- Stress And Anxiety: 3 people, 25.00%
- Diabetes: 3 people, 25.00%
- Cardiac Disorder: 2 people, 16.67%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
- Nausea (feeling of having an urge to vomit): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and Amphetamine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nexium (245,677 reports)
- Amphetamine (980 reports)
Browse all drug interactions of Nexium and Amphetamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amphetamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amphetamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium and amphetamine (the active ingredients of Nexium and Amphetamine, respectively), and Nexium and Amphetamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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