Nexium and Briviact drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Briviact (brivaracetam). Common drug interactions include chronic kidney disease among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Briviact. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

What is Briviact?

Briviact has active ingredients of brivaracetam. It is often used in epilepsy. eHealthMe is studying from 3,433 Briviact users. Check the latest studies of Briviact.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

17 people who take Nexium and Briviact together, and have interactions are studied.

Nexium and Briviact drug interactions.

What are the common drug interactions of Nexium and Briviact, by gender? *:

female:

  1. Chronic kidney disease
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  4. Leukoencephalopathy (disease of the white matter in the brain)
  5. Pancreatitis (inflammation of pancreas)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Renal failure (kidney dysfunction)

male:

  1. Death
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Adverse event
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Purpura (purplish discoloration of the skin)
  8. Rash pruritic (redness with itching)
  9. Respiratory tract infection
  10. Urinary tract infection

What are the common drug interactions of Nexium and Briviact, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Death
  2. Adverse event
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

10-19:

n/a

20-29:

n/a

30-39:

  1. Leukoencephalopathy (disease of the white matter in the brain)
  2. Pancreatitis (inflammation of pancreas)
  3. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  4. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

40-49:

  1. Chronic kidney disease
  2. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

  1. Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  3. Purpura (purplish discoloration of the skin)
  4. Rash pruritic (redness with itching)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 17.65%
  2. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 3 people, 17.65%
  3. Infantile Spasms: 2 people, 11.76%
  4. Stress And Anxiety: 2 people, 11.76%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 11.76%
  6. Rickets (softening of bones): 2 people, 11.76%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%
  8. High Blood Pressure: 1 person, 5.88%
  9. High Blood Cholesterol: 1 person, 5.88%
  10. Heart Attack: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and Briviact?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nexium and Briviact:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Briviact:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Briviact and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium and brivaracetam (the active ingredients of Nexium and Briviact, respectively), and Nexium and Briviact (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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