Niacin and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Niacin (niacin) and Plendil (felodipine). Common drug interactions include abdominal discomfort among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Niacin and Plendil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Niacin?

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 9,008 Niacin users. Check the latest studies of Niacin.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.



On Jul, 13, 2026

19 people who take Niacin and Plendil together, and have interactions are studied.

Niacin and Plendil drug interactions.

What are the common drug interactions of Niacin and Plendil, by gender? *:

female:

  1. Abdominal discomfort
  2. Abdominal pain upper
  3. Abscess jaw (tooth abscess or root abscess)
  4. Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
  5. Bone density decreased
  6. Cellulitis (infection under the skin)
  7. Deformity (disfigurement)
  8. Dental caries
  9. Dyspepsia (indigestion)
  10. Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)

male:

  1. Abdominal discomfort
  2. Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
  3. Swelling face
  4. Tenderness (pain or discomfort when an affected area is touched)
  5. Toothache (tooth pain)
  6. White blood cell count increased
  7. Wound dehiscence (a surgical incision reopens either internally or externally)
  8. Abscess jaw (tooth abscess or root abscess)
  9. Mastication disorder (disease of chewing food)
  10. Abdominal pain

What are the common drug interactions of Niacin and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Blood amylase increased
  3. Lipase increased
  4. Pancreatitis (inflammation of pancreas)
  5. Pancreatitis acute (sudden inflammation of pancreas)

40-49:

n/a

50-59:

n/a

60+:

  1. Tenderness (pain or discomfort when an affected area is touched)
  2. Arthralgia (joint pain)
  3. Abdominal discomfort
  4. Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Cellulitis (infection under the skin)
  7. Dental caries
  8. Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
  9. Gingival swelling (gums swelling)
  10. Groin pain

What are the existing conditions these people have? *

  1. Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 26.32%
  2. Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 10.53%
  3. Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.26%
  4. Pain: 1 person, 5.26%
  5. Osteoporosis (bones weak and more likely to break): 1 person, 5.26%
  6. Neuralgia (pain in one or more nerves): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Niacin and Plendil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Niacin and Plendil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Niacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Plendil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Niacin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plendil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on niacin and felodipine (the active ingredients of Niacin and Plendil, respectively), and Niacin and Plendil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: