Nicorette and Cisplatin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nicorette (nicotine polacrilex) and Cisplatin (cisplatin). Common drug interactions include supraventricular tachycardia among females and neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Nicorette and Cisplatin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Nicorette?
Nicorette has active ingredients of nicotine polacrilex. It is often used in quit smoking. eHealthMe is studying from 18,484 Nicorette users. Check the latest studies of Nicorette.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
18 people who take Nicorette and Cisplatin together, and have interactions are studied.

What are the common drug interactions of Nicorette and Cisplatin, by gender? *:
female:
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Anaemia (lack of blood)
- Dependence
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- International normalised ratio increased
- Pain
- Pain in extremity
male:
- Neutropenia (an abnormally low number of neutrophils)
- Infection
- Diarrhoea
- Disease progression
- Dizziness
- Dyspepsia (indigestion)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
What are the common drug interactions of Nicorette and Cisplatin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Renal failure acute (rapid kidney dysfunction)
50-59:
- White blood cell count decreased
- Infection
- Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- White blood cell count increased
- Neutropenia (an abnormally low number of neutrophils)
- Non-small cell lung cancer stage iiib
- Disease progression
- Anaemia (lack of blood)
- Dependence
60+:
- Anaemia of chronic disease
- Blood potassium decreased
- Hydropneumothorax (presence of both air and fluid in the pleural space (lungs))
- Mucosal inflammation (infection of mucous membrane)
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
- Performance status decreased
- Vomiting
- Back pain
- Blood bicarbonate increased
What are the existing conditions these people have? *
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 38.89%
- Non-Small Cell Lung Cancer Stage Iiib: 7 people, 38.89%
- Mood Swings (an extreme or rapid change in mood): 7 people, 38.89%
- High Blood Pressure: 7 people, 38.89%
- High Blood Cholesterol: 7 people, 38.89%
- Cellulitis (infection under the skin): 3 people, 16.67%
- Non-Small Cell Lung Cancer Stage I: 2 people, 11.11%
- Back Pain: 2 people, 11.11%
- Nicotine Dependence: 1 person, 5.56%
- Lung Cancer - Non-Small Cell (lung cancer): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Nicorette and Cisplatin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nicorette and Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nicorette:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nicorette and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on nicotine polacrilex and cisplatin (the active ingredients of Nicorette and Cisplatin, respectively), and Nicorette and Cisplatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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