Nicotine and Centrum silver drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include drug ineffective among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Centrum silver. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.



On Jul, 08, 2026

33 people who take Nicotine and Centrum silver together, and have interactions are studied.

Nicotine and Centrum silver drug interactions.

What are the common drug interactions of Nicotine and Centrum Silver, by gender? *:

female:

  1. Drug ineffective
  2. Fall
  3. Lumbar radiculopathy (radicular pain in the low back and legs)
  4. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  5. Synovial cyst (cyst of joint filled with synovial fluid)
  6. Headache (pain in head)
  7. Hot flush (sudden feelings of heat)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Blood pressure increased
  10. Bone density decreased

male:

  1. Pain
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Tendonitis (a condition that causes pain and swelling of tendons)
  4. Aphasia (damage to the parts of the brain that control language)
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  6. Cellulitis (infection under the skin)
  7. Confusional state
  8. Death
  9. Disability
  10. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Nicotine and Centrum Silver, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug ineffective
  2. Narcotic intoxication (a condition caused by use of narcotic agents)

50-59:

  1. Pain
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  5. Cellulitis (infection under the skin)
  6. Cholecystitis (infection of gallbladder)
  7. Chronic kidney disease
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Fall
  10. Histoplasmosis disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum)

60+:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Femur fracture
  4. Head injury
  5. Overdose
  6. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  7. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  8. Visual field defect
  9. Blood pressure increased
  10. Bone density decreased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 42.42%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 30.30%
  3. Wheezing (a high-pitched whistling sound made while you breath): 7 people, 21.21%
  4. Pain: 6 people, 18.18%
  5. Muscle Spasms (muscle contraction): 6 people, 18.18%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 18.18%
  7. Pain In Extremity: 5 people, 15.15%
  8. Oral Herpes (viral infection of mouth): 5 people, 15.15%
  9. Mononeuropathy (a type of damage to nerves outside the brain and spinal cord): 5 people, 15.15%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nicotine and Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nicotine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nicotine and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Nicotine and Centrum silver, respectively), and Nicotine and Centrum silver (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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