Nicotine and Lamisil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nicotine (nicotine) and Lamisil (terbinafine hydrochloride). Common drug interactions include type 2 diabetes mellitus among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Nicotine and Lamisil. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Nicotine?
Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.
What is Lamisil?
Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.
24 people who take Nicotine and Lamisil together, and have interactions are studied.

What are the common drug interactions of Nicotine and Lamisil, by gender? *:
female:
- Type 2 diabetes mellitus
- Arthralgia (joint pain)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Chest pain
- Cough
- Dental caries
- Depression
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diarrhoea
- Drug dependence
male:
- Depression
- Suicidal ideation
- Ankle fracture
- Bone density decreased
- Confusional state
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Lung disorder (lung disease)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Renal failure (kidney dysfunction)
- Somnolence (a state of near-sleep, a strong desire for sleep)
What are the common drug interactions of Nicotine and Lamisil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Ankle fracture
- Arthralgia (joint pain)
- Chest pain
- Confusional state
- Cough
- Dental caries
- Depression
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diarrhoea
- Drug dependence
40-49:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Abnormal weight gain
- Blood cholesterol increased
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Erythema (redness of the skin)
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- General physical health deterioration (weak health status)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Joint contracture (a permanent shortening of a muscle or joint)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Chronic kidney disease
- Depression
- Emotional distress
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Suicidal ideation
- Bone density decreased
- Renal failure (kidney dysfunction)
60+:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Lip blister
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Rash
- Swelling face
- Swollen tongue (swelling of tongue)
- Face oedema (swelling of face)
- Leukocytosis (increased white blood cells)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 41.67%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 37.50%
- Hiv Infection: 4 people, 16.67%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 12.50%
- Pain: 3 people, 12.50%
- Stress And Anxiety: 2 people, 8.33%
- Pneumonia: 2 people, 8.33%
- Nuclear Magnetic Resonance Imaging Brain: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Nicotine and Lamisil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nicotine and Lamisil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nicotine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lamisil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nicotine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamisil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nicotine and terbinafine hydrochloride (the active ingredients of Nicotine and Lamisil, respectively), and Nicotine and Lamisil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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