Nicotine and Trulicity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Trulicity (dulaglutide). Common drug interactions include loss of consciousness among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Trulicity. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

On Jul, 06, 2026

24 people who take Nicotine and Trulicity together, and have interactions are studied.

Nicotine and Trulicity drug interactions.

What are the common drug interactions of Nicotine and Trulicity, by gender? *:

female:

Loss of consciousness
Muscle twitching
Vomiting
Hidradenitis (chronic disease of a type of sweat gland)
Peripheral swelling
Abdominal distension
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bowel movement irregularity
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dry mouth

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis (infection under the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Abscess limb (limb infection)
Anal abscess
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Genital abscess (build up of pus in genital)

What are the common drug interactions of Nicotine and Trulicity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain
Groin abscess (pus in groin)
Nerve injury
Scar
Abscess limb (limb infection)
Anal abscess
Asthenia (weakness)
Back pain
Cellulitis (infection under the skin)
Genital abscess (build up of pus in genital)

40-49:

Cellulitis (infection under the skin)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Perineal abscess
Rectal abscess (pus in rectum)
Scrotal abscess (pus in scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hepatomegaly (abnormal enlargement of the liver)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Skin cancer
Skin ulcer
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Acute myocardial infarction (acute heart attack)
Pulmonary embolism (blockage of the main artery of the lung)
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Respiratory disorder (respiratory disease)
Respiratory distress (difficulty in breathing)
Sepsis (a severe blood infection that can lead to organ failure and death)
Chronic kidney disease
Diarrhoea

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 16.67%
Weight Decreased: 3 people, 12.50%
Type 2 Diabetes: 3 people, 12.50%
Hypotension (abnormally low blood pressure): 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
Hypersensitivity: 2 people, 8.33%
Hidradenitis (chronic disease of a type of sweat gland): 2 people, 8.33%
Cardiac Failure: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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