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Nilutamide and Lupron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nilutamide (nilutamide) and Lupron (leuprolide acetate). Common drug interactions include prostatic specific antigen increased among males.

The phase IV clinical study analyzes what interactions people have when they take Nilutamide and Lupron. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Nilutamide?

Nilutamide has active ingredients of nilutamide. eHealthMe is studying from 223 Nilutamide users. Check the latest studies of Nilutamide.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

On Jul, 06, 2026

26 people who take Nilutamide and Lupron together, and have interactions are studied.

Nilutamide and Lupron drug interactions.

What are the common drug interactions of Nilutamide and Lupron, by gender? *:

female:

n/a

male:

  1. Prostatic specific antigen increased
  2. Arthralgia (joint pain)
  3. Initial insomnia (feeling of inadequate or poor-quality sleep)
  4. Insomnia (sleeplessness)
  5. Abnormal dreams
  6. Pain in extremity
  7. Fatigue (feeling of tiredness)
  8. Decreased interest
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Nilutamide and Lupron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Death

60+:

  1. Prostatic specific antigen increased
  2. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  3. Initial insomnia (feeling of inadequate or poor-quality sleep)
  4. Insomnia (sleeplessness)
  5. Abnormal dreams
  6. Pain in extremity
  7. Fatigue (feeling of tiredness)
  8. Decreased interest
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

  1. Prostate Cancer: 16 people, 61.54%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Nilutamide and Lupron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nilutamide and Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nilutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lupron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nilutamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lupron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on nilutamide and leuprolide acetate (the active ingredients of Nilutamide and Lupron, respectively), and Nilutamide and Lupron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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