Nitrous oxide and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrous oxide (nitrous oxide) and Prednisolone (prednisolone). Common drug interactions include lipodystrophy acquired among females and lipodystrophy acquired among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrous oxide and Prednisolone. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrous oxide?

Nitrous oxide has active ingredients of nitrous oxide. eHealthMe is studying from 1,780 Nitrous oxide users. Check the latest studies of Nitrous oxide.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

On Jul, 26, 2026

71 people who take Nitrous oxide and Prednisolone together, and have interactions are studied.

Nitrous oxide and Prednisolone drug interactions.

What are the common drug interactions of Nitrous Oxide and Prednisolone, by gender? *:

female:

Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
Anal atresia (anus is either not present or it is in the wrong place)
Blood iron decreased
Erythema (redness of the skin)
Genitalia external ambiguous (external genitals don't appear to be clearly either male or female)
Premature baby
Gastrointestinal malformation
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

male:

Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Mean cell volume decreased (less of the average red blood cell volume)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Abnormal behaviour
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anal atresia (anus is either not present or it is in the wrong place)
Blood iron decreased
Caudal regression syndrome (disorder that impairs the development of the lower (caudal) half of the body)
Compulsive shopping

What are the common drug interactions of Nitrous Oxide and Prednisolone, by age (0-1 to 60+)? *:

0-1:

Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Premature baby
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Anal atresia (anus is either not present or it is in the wrong place)
Blood iron decreased
Erythema (redness of the skin)
Gastrointestinal malformation
Genitalia external ambiguous (external genitals don't appear to be clearly either male or female)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

Anal atresia (anus is either not present or it is in the wrong place)
Blood iron decreased
Caudal regression syndrome (disorder that impairs the development of the lower (caudal) half of the body)
Erythema (redness of the skin)
Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gastrointestinal malformation
Genitalia external ambiguous (external genitals don't appear to be clearly either male or female)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Musculoskeletal deformity (functional disability of the body's muscles, joints, tendons, ligaments and nerves)

20-29:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Premature labour
Circulatory collapse
Dizziness
Gestational diabetes (diabetes in pregnancy)
Haemoglobin decreased
Loss of consciousness
Lymphocyte count decreased
Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)

30-39:

Drug ineffective
Maternal exposure during pregnancy (use of substance during pregnancy)
Spinal epidural haematoma (blood clot into the epidural space in the spine)
Dystonia (abnormal muscle tone)
Live birth

40-49:

Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Premature labour
Gestational diabetes (diabetes in pregnancy)
Maternal exposure during pregnancy (use of substance during pregnancy)
Ataxia (loss of full control of bodily movements)
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Gait disturbance
Live birth
Alanine aminotransferase increased

50-59:

n/a

60+:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Premature labour
Alanine aminotransferase increased
Aspartate aminotransferase increased
Gestational diabetes (diabetes in pregnancy)
Decreased appetite
Maternal exposure during pregnancy (use of substance during pregnancy)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Hiv Infection: 64 people, 90.14%
Gestational Diabetes (diabetes in pregnancy): 61 people, 85.92%
Anencephaly (absence of a major portion of the brain, skull, and scalp that occurs during embryonic development): 4 people, 5.63%

* Approximation only. Some reports may have incomplete information.

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