Nolvadex and Chantix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nolvadex (tamoxifen citrate) and Chantix (varenicline tartrate). Common drug interactions include emotional distress among females and cholecystitis among males.

The phase IV clinical study analyzes what interactions people have when they take Nolvadex and Chantix. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Nolvadex?

Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

On Jul, 11, 2026

29 people who take Nolvadex and Chantix together, and have interactions are studied.

What are the common drug interactions of Nolvadex and Chantix, by gender? *:

female:

Emotional distress
Sinusitis (inflammation of sinus)
Accident
Bone loss
Chest pain
Laceration (tearing of soft body tissue)
Oedema peripheral (superficial swelling)
Fatigue (feeling of tiredness)
Gait disturbance
Hot flush (sudden feelings of heat)

male:

Cholecystitis (infection of gallbladder)
Asthma
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Neutropenia (an abnormally low number of neutrophils)
Pancreatitis (inflammation of pancreas)
Pneumonia
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the common drug interactions of Nolvadex and Chantix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Arthralgia (joint pain)
Back pain
Bone disorder
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Cervix carcinoma (cancer of cervix)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Delusion (a false belief or opinion)
Depression
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

40-49:

Blood pressure increased
Bradycardia (abnormally slow heart action)
Dizziness
Fall
Hypotension (abnormally low blood pressure)
Pain in extremity
Speech disorder

50-59:

Appetite disorder (abnormal eating habits)
Asthenia (weakness)
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bone disorder
Bone erosion
Cardiac murmur (an heart sound in valve abnormality)
Chest pain
Chills (felling of cold)
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
Decreased interest

60+:

Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Ataxia (loss of full control of bodily movements)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Biliary dilatation
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone loss
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Sleep Apnea Syndrome: 14 people, 48.28%
Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 31.03%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9 people, 31.03%
Neuropathy Peripheral (surface nerve damage): 7 people, 24.14%
Metastases To Bone (cancer spreads to bone): 6 people, 20.69%
Bone Loss: 4 people, 13.79%
Bone Density Decreased: 4 people, 13.79%
Pain: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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