Northera and Valacyclovir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Northera (droxidopa) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include heart rate increased among females and blood pressure increased among males.
The phase IV clinical study analyzes what interactions people have when they take Northera and Valacyclovir. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Northera?
Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.
What is Valacyclovir?
Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.
36 people who take Northera and Valacyclovir together, and have interactions are studied.

What are the common drug interactions of Northera and Valacyclovir, by gender? *:
female:
- Heart rate increased
- Hypertension (high blood pressure)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Asthenia (weakness)
- Dizziness
- Fall
- Fatigue (feeling of tiredness)
- Head injury
- Headache (pain in head)
male:
- Blood pressure increased
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Acute myocardial infarction (acute heart attack)
- Adverse reaction
- Alanine aminotransferase increased
- Blood glucose increased
- Death
- Diarrhoea
- Drug ineffective
- Dysuria (painful or difficult urination)
What are the common drug interactions of Northera and Valacyclovir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anaemia (lack of blood)
- Exostosis (formation of new bone on the surface of a bone)
- Hyperthyroidism (over activity of the thyroid gland)
- Incontinence (lack of moderation or self-control)
- Intervertebral disc protrusion (spinal disc protrusion)
- Alanine aminotransferase increased
- Blood glucose increased
- Diarrhoea
- Drug ineffective
- Dysuria (painful or difficult urination)
40-49:
- Heart rate increased
- Hypertension (high blood pressure)
- Vomiting
- Asthenia (weakness)
- Fall
- Fatigue (feeling of tiredness)
- Head injury
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
50-59:
- Blood potassium decreased
- Electrocardiogram qt prolonged
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Adverse reaction
- Anxiety
- Balance disorder
- Malaise (a feeling of general discomfort or uneasiness)
60+:
- Blood pressure increased
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Pneumonia
- Pulmonary congestion (congestion in the lungs)
- Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Hypersomnia (excessive daytime sleepiness (eds))
- Foot amputation (loss of foot)
- Acute myocardial infarction (acute heart attack)
- Death
What are the existing conditions these people have? *
- Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 13 people, 36.11%
- Hypotension (abnormally low blood pressure): 6 people, 16.67%
- Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 5 people, 13.89%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 11.11%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 11.11%
- Parkinson's Disease: 3 people, 8.33%
- Hallucinations (sensations that appear real but are created by your mind): 3 people, 8.33%
- Delusion (a false belief or opinion): 3 people, 8.33%
- Autonomic Nervous System Imbalance (autonomic nervous system is of net equal emphasis): 3 people, 8.33%
- Constipation: 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Northera and Valacyclovir?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Northera (22,874 reports)
- Valacyclovir (42,107 reports)
Browse all drug interactions of Northera and Valacyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Northera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valacyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Northera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valacyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on droxidopa and valacyclovir hydrochloride (the active ingredients of Northera and Valacyclovir, respectively), and Northera and Valacyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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