Abraxane and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abraxane (paclitaxel) and Restoril (temazepam). Common drug interactions include osteonecrosis of jaw among females and cystoid macular oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Abraxane and Restoril. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 07, 2026

22 people who take Abraxane and Restoril together, and have interactions are studied.

Abraxane and Restoril drug interactions.

What are the common drug interactions of Abraxane and Restoril, by gender? *:

female:

Osteonecrosis of jaw (death of bone of jaw)
Chills (felling of cold)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Pain
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Injury
Abdominal pain
Arthralgia (joint pain)
Depression

male:

Cystoid macular oedema (fluid accumulation after cataract surgery)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypophysitis (inflammation of the pituitary gland)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)

What are the common drug interactions of Abraxane and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Abdominal distension
Abdominal pain
Abscess jaw (tooth abscess or root abscess)
Acute respiratory failure
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)

50-59:

Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hepatomegaly (abnormal enlargement of the liver)
Nausea (feeling of having an urge to vomit)
Splenomegaly (enlargement of spleen)
Brain neoplasm malignant (brain cancer tumour)
Cervicobrachial syndrome (pain in neck and arm with changing location)
Loss of consciousness
Malignant neoplasm of spinal cord (cancer tumour of spinal cord)
Spinal osteoarthritis (joint cartilage loss in spine)
Atelectasis (partial or complete collapse of the lung)

60+:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Hair colour changes
Hair disorder
Abscess limb (limb infection)
Anaemia (lack of blood)
Blood creatinine increased
Body temperature increased
Breast inflammation
Breast pain

What are the existing conditions these people have? *

Pain: 4 people, 18.18%
Nausea (feeling of having an urge to vomit): 4 people, 18.18%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 9.09%
Rashes (redness): 2 people, 9.09%
Pneumonia: 2 people, 9.09%
Nausea And Vomiting: 2 people, 9.09%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 9.09%
Indigestion: 2 people, 9.09%
Dyspnea (difficult or laboured breathing): 2 people, 9.09%
Diarrhea: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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