Novolog and Zantac 150 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novolog (insulin aspart recombinant) and Zantac 150 (ranitidine hydrochloride). Common drug interactions include kidney infection among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Novolog and Zantac 150. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Novolog?

Novolog has active ingredients of insulin aspart recombinant. It is often used in diabetes. eHealthMe is studying from 56,160 Novolog users. Check the latest studies of Novolog.

What is Zantac 150?

Zantac 150 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,519 Zantac 150 users. Check the latest studies of Zantac 150.

On Jul, 18, 2026

55 people who take Novolog and Zantac 150 together, and have interactions are studied.

Novolog and Zantac 150 drug interactions.

What are the common drug interactions of Novolog and Zantac 150, by gender? *:

female:

Kidney infection
Memory impairment
Muscle disorder (muscle disease)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Nausea (feeling of having an urge to vomit)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pancreatitis acute (sudden inflammation of pancreas)
Panic attack
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Renal disorder (kidney disease)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cardiac arrest
Cardiac failure acute
Decreased appetite
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fungal sepsis (whole body infection by fungus)
Headache (pain in head)
Lung infection
Pneumonia

What are the common drug interactions of Novolog and Zantac 150, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hypersensitivity

20-29:

n/a

30-39:

Depressed level of consciousness
Dyspnoea (difficult or laboured respiration)
Eye infection
Fibrin degradation products increased
General physical health deterioration (weak health status)
Glycosylated haemoglobin increased
Hyperhidrosis (abnormally increased sweating)
Infection in an immunocompromised host
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Meningitis listeria (a bacterial infection of the membranes covering the brain and spinal cord (meninges))

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Diabetic complication
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hyperkalaemia (damage to or disease of the kidney)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Nephrogenic anaemia (anaemia due to kidney disease)
Death
Anxiety
Depression

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Nephropathy (damage to or disease of a kidney)
Blood glucose increased
Death
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired gastric emptying
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight decreased
Alanine aminotransferase increased
Alveolitis (inflammation in the socket of a tooth)
Application site erythema (redness of the skin at application site)
Application site inflammation
Application site pain
Aspartate aminotransferase increased

What are the existing conditions these people have? *

Pain: 29 people, 52.73%
High Blood Pressure: 26 people, 47.27%
Depression: 21 people, 38.18%
High Blood Cholesterol: 18 people, 32.73%
Infection: 16 people, 29.09%
Blood Pressure Abnormal: 14 people, 25.45%
Multiple Allergies (allergy to multiple agents): 11 people, 20.00%
Nausea (feeling of having an urge to vomit): 10 people, 18.18%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 18.18%
Insomnia (sleeplessness): 9 people, 16.36%

* Approximation only. Some reports may have incomplete information.

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