Noxafil and Ibuprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Noxafil (posaconazole) and Ibuprofen (ibuprofen). Common drug interactions include abdominal pain upper among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Noxafil and Ibuprofen. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Noxafil?

Noxafil has active ingredients of posaconazole. eHealthMe is studying from 5,919 Noxafil users. Check the latest studies of Noxafil.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

On Jul, 15, 2026

36 people who take Noxafil and Ibuprofen together, and have interactions are studied.

Noxafil and Ibuprofen drug interactions.

What are the common drug interactions of Noxafil and Ibuprofen, by gender? *:

female:

Abdominal pain upper
Drug half-life increased
Nausea (feeling of having an urge to vomit)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Vomiting
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Alanine aminotransferase increased
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adverse drug reaction

male:

Febrile neutropenia (fever with reduced white blood cells)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Quality of life decreased
Renal failure (kidney dysfunction)
Renal pain (kidney pain)
Sinusitis (inflammation of sinus)
Spinal fracture (fracture in one of vertebrae)
Wrist fracture
C-reactive protein increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

What are the common drug interactions of Noxafil and Ibuprofen, by age (0-1 to 60+)? *:

0-1:

Deafness unilateral
Hand-foot-and-mouth disease
Infection
Parainfluenzae virus infection

2-9:

Febrile neutropenia (fever with reduced white blood cells)
Encephalitis (inflammation of the brain)

10-19:

C-reactive protein increased
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Interleukin level increased
Liver disorder (liver diseases)
Myalgia (muscle pain)
Pyrexia (fever)
Sepsis (a severe blood infection that can lead to organ failure and death)
Serum ferritin increased
Somnolence (a state of near-sleep, a strong desire for sleep)
Vision blurred

20-29:

Drug half-life increased
Nausea (feeling of having an urge to vomit)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Vomiting
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypoacusis (loss of hearing)
Tinnitus (a ringing in the ears)
Aphasia (damage to the parts of the brain that control language)
Chills (felling of cold)

30-39:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Atrioventricular block second degree (heart block second degree)
Nodal arrhythmia (an irregular heart beat originating from within the atrioventricular node)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)

40-49:

n/a

50-59:

Blood potassium decreased

60+:

Febrile neutropenia (fever with reduced white blood cells)
Abdominal pain upper
Pneumonia
Pyrexia (fever)
Alanine aminotransferase increased
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
General physical health deterioration (weak health status)
Asthenia (weakness)
Death
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 25.00%
High Blood Pressure: 6 people, 16.67%
Fungal Infection: 6 people, 16.67%
Nausea (feeling of having an urge to vomit): 5 people, 13.89%
Immunodeficiency: 5 people, 13.89%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.11%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 11.11%
Fever: 4 people, 11.11%
Neuropathy Peripheral (surface nerve damage): 3 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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