Nuvaring and Maxzide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvaring (ethinyl estradiol; etonogestrel) and Maxzide (hydrochlorothiazide; triamterene). Common drug interactions include dysarthria among females.

The phase IV clinical study analyzes what interactions people have when they take Nuvaring and Maxzide. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

What is Maxzide?

Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

14 people who take Nuvaring and Maxzide together, and have interactions are studied.

What are the common drug interactions of Nuvaring and Maxzide, by gender? *:

female:

Dysarthria (speech disorder)
Facial paralysis (loss of function of face muscle)
Leiomyoma (a noncancerous (benign) tumour made up mostly of smooth muscle cells)
Poor quality sleep
Tricuspid valve incompetence (inefficient heart valve)
Asthma
Atelectasis (partial or complete collapse of the lung)
Drug ineffective
Fall
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

male:

n/a

What are the common drug interactions of Nuvaring and Maxzide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fall
Leiomyoma (a noncancerous (benign) tumour made up mostly of smooth muscle cells)
Ligament sprain (ligament stretched)
Maternal exposure during pregnancy (use of substance during pregnancy)
Ovarian cyst (fluid filled sac of the ovary)
Pain in extremity
Pericardial effusion (fluid around the heart)
Pericarditis (inflammation of the pericardium)
Pleural effusion (water on the lungs)

30-39:

n/a

40-49:

Dysarthria (speech disorder)
Facial paralysis (loss of function of face muscle)
Hemiparesis (weakness on one side of the body)
Migraine (headache)
Poor quality sleep
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
Pneumonia

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 71.43%
Oedema Peripheral (superficial swelling): 2 people, 14.29%
Migraine (headache): 1 person, 7.14%
Drowsiness: 1 person, 7.14%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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