Ofev and Norvasc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofev (nintedanib esylate) and Norvasc (amlodipine besylate). Common drug interactions include dizziness among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Ofev and Norvasc. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

On Jul, 19, 2026

93 people who take Ofev and Norvasc together, and have interactions are studied.

What are the common drug interactions of Ofev and Norvasc, by gender? *:

female:

Dizziness
Fall
Dyspnoea exertional (breathlessness or shortness of breath)
Abdominal discomfort
Chest pain
Decreased appetite
Productive cough
Asthenia (weakness)
Urinary tract infection
Constipation

male:

Diarrhoea
Cough
Dizziness
Anxiety
Asthenia (weakness)
Fatigue (feeling of tiredness)
Atelectasis (partial or complete collapse of the lung)
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

What are the common drug interactions of Ofev and Norvasc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebral artery stenosis (hardening of brain blood vessels)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chest pain
Chronic kidney disease
Depression
Dilated cardiomyopathy
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Ejection fraction decreased (systolic heart failure)

30-39:

n/a

40-49:

n/a

50-59:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Joint swelling
Osteoporosis (bones weak and more likely to break)
Postoperative wound infection
Thrombosis (formation of a blood clot inside a blood vessel)

60+:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Dizziness
Fall
Weight decreased
Dyspnoea exertional (breathlessness or shortness of breath)
Abdominal pain upper
Asthenia (weakness)
Peripheral swelling
Death

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 67 people, 72.04%
High Blood Cholesterol: 10 people, 10.75%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 9.68%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 8.60%
Chest Pain: 6 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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