Ondansetron and Midostaurin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ondansetron (ondansetron) and Midostaurin (midostaurin). Common drug interactions include pneumonia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Ondansetron and Midostaurin. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 122,738 Ondansetron users. Check the latest studies of Ondansetron.

What is Midostaurin?

Midostaurin has active ingredients of midostaurin. eHealthMe is studying from 1,137 Midostaurin users. Check the latest studies of Midostaurin.



On Jul, 18, 2026

55 people who take Ondansetron and Midostaurin together, and have interactions are studied.

Ondansetron and Midostaurin drug interactions.

What are the common drug interactions of Ondansetron and Midostaurin, by gender? *:

female:

  1. Pneumonia
  2. Klebsiella infection
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Septic shock (shock due to blood infection)
  5. Constipation
  6. Myelosuppression (a decrease in the production of blood cells)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Drug intolerance (drug sensitivity)

male:

  1. Pneumonia
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Back pain
  5. Diarrhoea
  6. Dyspnoea (difficult or laboured respiration)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Haemorrhage intracranial (bleeding within the skull)
  9. Lethargy (tiredness)
  10. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Ondansetron and Midostaurin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Febrile neutropenia (fever with reduced white blood cells)

20-29:

  1. Anxiety
  2. Insomnia (sleeplessness)

30-39:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Cardiac failure acute
  3. Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
  4. Septic shock (shock due to blood infection)
  5. Haematochezia (passage of stools containing blood)

40-49:

  1. Pneumonia
  2. Thrombocytopenia (decrease of platelets in blood)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Haemorrhage intracranial (bleeding within the skull)
  5. Anaemia (lack of blood)
  6. Cardiac failure
  7. Ejection fraction decreased (systolic heart failure)
  8. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  9. Hypersplenism (enlarged spleen and a decrease in one or more types of blood cells)
  10. Malignant neoplasm progression (cancer tumour came back)

50-59:

  1. Constipation
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Klebsiella infection
  4. Myelosuppression (a decrease in the production of blood cells)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Septic shock (shock due to blood infection)
  7. Pneumonia
  8. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  9. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  10. Hypokalaemia (low potassium)

60+:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Pneumonia
  3. Anal abscess
  4. Dehydration (dryness resulting from the removal of water)
  5. Weight increased
  6. Abdominal pain upper
  7. Back pain
  8. Cholecystitis (infection of gallbladder)
  9. Eating disorder
  10. Escherichia sepsis (bacterial infection by escherichia coli)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 34 people, 61.82%
  2. Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 14 people, 25.45%
  3. Febrile Neutropenia (fever with reduced white blood cells): 10 people, 18.18%
  4. Insomnia (sleeplessness): 8 people, 14.55%
  5. Pain: 7 people, 12.73%
  6. Nausea And Vomiting: 7 people, 12.73%
  7. Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 12.73%
  8. Diarrhea: 6 people, 10.91%
  9. Leukocytosis (increased white blood cells): 5 people, 9.09%
  10. Stress And Anxiety: 5 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ondansetron and Midostaurin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ondansetron and Midostaurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ondansetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Midostaurin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ondansetron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Midostaurin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron and midostaurin (the active ingredients of Ondansetron and Midostaurin, respectively), and Ondansetron and Midostaurin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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