Oracea and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Oracea (doxycycline) and Clonazepam (clonazepam). Common drug interactions include chronic kidney disease among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Oracea and Clonazepam. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Oracea?
Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
19 people who take Oracea and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Oracea and Clonazepam, by gender? *:
female:
- Chronic kidney disease
- Headache (pain in head)
- Blood pressure increased
- Sinusitis (inflammation of sinus)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Hypertension (high blood pressure)
- Alopecia (absence of hair from areas of the body)
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Hypersensitivity
male:
- Drug ineffective
- Swelling
- Fatigue (feeling of tiredness)
- Furuncle (infection of the hair follicle)
- Headache (pain in head)
- Hypersensitivity
- Nervousness
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Oedema (fluid collection in tissue)
What are the common drug interactions of Oracea and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Eye pain
- Headache (pain in head)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
20-29:
- Abscess (pus)
- Blood lactate dehydrogenase increased
- Depression
- Discomfort
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Furuncle (infection of the hair follicle)
- Hypersensitivity
30-39:
- Headache (pain in head)
- Hypersensitivity
- Hypoaesthesia (reduced sense of touch or sensation)
- Throat tightness
40-49:
- Sinusitis (inflammation of sinus)
50-59:
n/a
60+:
- Chronic kidney disease
- Headache (pain in head)
- Blood pressure increased
- Hypertension (high blood pressure)
- Oral herpes (viral infection of mouth)
What are the existing conditions these people have? *
- Acne (skin problems that cause pimples): 5 people, 26.32%
- Depression: 5 people, 26.32%
- Asthma: 4 people, 21.05%
- Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 4 people, 21.05%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 15.79%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 15.79%
- Gouty Arthritis (joint inflammation with crystal formation): 3 people, 15.79%
- Gingivitis (inflammation of gums): 3 people, 15.79%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
* Approximation only. Some reports may have incomplete information.
Do you take Oracea and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Oracea (1,272 reports)
- Clonazepam (146,270 reports)
Browse all drug interactions of Oracea and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Oracea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Oracea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on doxycycline and clonazepam (the active ingredients of Oracea and Clonazepam, respectively), and Oracea and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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