Oracea and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oracea (doxycycline) and Flonase (fluticasone propionate). Common drug interactions include neuralgia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Oracea and Flonase. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Jul, 11, 2026

30 people who take Oracea and Flonase together, and have interactions are studied.

What are the common drug interactions of Oracea and Flonase, by gender? *:

female:

Neuralgia (pain in one or more nerves)
Pain
Weight increased
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Adverse drug reaction
Anxiety
Drug ineffective
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Injection site pain
Stress

What are the common drug interactions of Oracea and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Injection site pain
Stress

40-49:

Cataract (clouding of the lens inside the eye)
Drug administration error
Drug ineffective
Injection site erythema (redness at injection site)
Injection site hypertrophy (enlargement of an organ or tissue from the increase in size of its cells at injection site)
Injection site pain
Injection site rash
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Metrorrhagia (uterine bleeding at irregular intervals)
Nausea (feeling of having an urge to vomit)

50-59:

Rash
Skin irritation
Anxiety
Appendicitis (inflammation of the appendix)
Chronic kidney disease
Disturbance in attention
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle tightness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Intervertebral disc protrusion (spinal disc protrusion)
Spinal compression fracture (fracture due to spinal compression on bone)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 56.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 26.67%
Hypersensitivity: 5 people, 16.67%
High Blood Pressure: 4 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.67%
Pain: 2 people, 6.67%
High Blood Cholesterol: 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Fatigue (feeling of tiredness): 2 people, 6.67%
Depression: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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