Oracea and Xanax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oracea (doxycycline) and Xanax (alprazolam). Common drug interactions include migraine among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Oracea and Xanax. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Oracea?

Oracea has active ingredients of doxycycline. It is often used in rosacea. eHealthMe is studying from 1,272 Oracea users. Check the latest studies of Oracea.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

On Jul, 18, 2026

37 people who take Oracea and Xanax together, and have interactions are studied.

What are the common drug interactions of Oracea and Xanax, by gender? *:

female:

Migraine (headache)
Abdominal pain upper
Depression
Fibromyalgia (a long-term condition which causes pain all over the body)
Food intolerance (inability to have food)
Irritable bowel syndrome
Memory impairment
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Nausea (feeling of having an urge to vomit)
Loss of consciousness

male:

Erythema (redness of the skin)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Feeling hot
Flushing (the warm, red condition of human skin)
Furuncle (infection of the hair follicle)
Hypersensitivity
Nervousness

What are the common drug interactions of Oracea and Xanax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abscess (pus)
Blood lactate dehydrogenase increased
Depression
Discomfort
Dizziness
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Furuncle (infection of the hair follicle)
Hypersensitivity

30-39:

Drug ineffective
Pain
Suicidal ideation
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

40-49:

Drug ineffective
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac myxoma (tumour of the heart in adults)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Post-traumatic stress disorder
Exostosis (formation of new bone on the surface of a bone)
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Erythema (redness of the skin)
Pain of skin
Rash papular (redness with papule)
Rebound effect (take-back effect)

60+:

Abdominal pain upper
Clostridial infection (infectious conditions by clostridium bacteria)
Loss of consciousness
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Renal tubular necrosis (death of kidney tubules)
Diarrhoea
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Acute respiratory failure
Cardiac arrest
Dizziness

What are the existing conditions these people have? *

Drowsiness: 16 people, 43.24%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 21.62%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.11%
Chest Pain: 3 people, 8.11%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 5.41%
Motion Sickness (travel sickness): 2 people, 5.41%
High Blood Pressure: 2 people, 5.41%
High Blood Cholesterol: 2 people, 5.41%
Depression: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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