Orenitram and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Orenitram (treprostinil) and Clonazepam (clonazepam). Common drug interactions include oxygen saturation decreased among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Orenitram and Clonazepam. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Orenitram?
Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
48 people who take Orenitram and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Orenitram and Clonazepam, by gender? *:
female:
- Oxygen saturation decreased
- Rhinorrhoea (watery mucus discharge from the nose)
- Seasonal allergy (allergic condition due to certain season)
- Sneezing
- Abdominal distension
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Erythema (redness of the skin)
- Oedema (fluid collection in tissue)
male:
- Headache (pain in head)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Constipation
- Diarrhoea
- Peripheral swelling
- Back pain
- Chest pain
- Fatigue (feeling of tiredness)
- Flushing (the warm, red condition of human skin)
- Apnoea (suspension of external breathing)
What are the common drug interactions of Orenitram and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Sinusitis (inflammation of sinus)
- Fatigue (feeling of tiredness)
- Flushing (the warm, red condition of human skin)
- Pain in extremity
- Joint swelling
- Memory impairment
- Oedema peripheral (superficial swelling)
- Diarrhoea
- Drug hypersensitivity
- Ear infection
40-49:
n/a
50-59:
- Nausea (feeling of having an urge to vomit)
- Headache (pain in head)
- Fatigue (feeling of tiredness)
- Myalgia (muscle pain)
- Pain in jaw
- Diarrhoea
- Abdominal pain upper
- Flushing (the warm, red condition of human skin)
- Malaise (a feeling of general discomfort or uneasiness)
- Anaemia (lack of blood)
60+:
- Weight decreased
- Dyspnoea (difficult or laboured respiration)
- Peripheral coldness
- Peripheral swelling
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cellulitis (infection under the skin)
- Concussion (short loss of normal brain function in response to a head injury)
- Lung neoplasm malignant (cancer tumour of lung)
- Physical assault
- Arthralgia (joint pain)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 42 people, 87.50%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 18.75%
* Approximation only. Some reports may have incomplete information.
Do you take Orenitram and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Orenitram (17,714 reports)
- Clonazepam (146,270 reports)
Browse all drug interactions of Orenitram and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Orenitram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Orenitram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on treprostinil and clonazepam (the active ingredients of Orenitram and Clonazepam, respectively), and Orenitram and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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