Orenitram and Clopidogrel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Orenitram (treprostinil) and Clopidogrel (clopidogrel). Common drug interactions include cardiac failure congestive among females and pain in jaw among males.
The phase IV clinical study analyzes what interactions people have when they take Orenitram and Clopidogrel. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Orenitram?
Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.
33 people who take Orenitram and Clopidogrel together, and have interactions are studied.

What are the common drug interactions of Orenitram and Clopidogrel, by gender? *:
female:
- Cardiac failure congestive
- Cardiomegaly (increased size of heart than normal)
- Chronic kidney disease
- Diastolic dysfunction
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Hypochromasia (an anaemic condition)
- Mitral valve incompetence (inefficient heart valve)
- Pericardial effusion (fluid around the heart)
male:
- Pain in jaw
- Pain in extremity
- Dyspnoea (difficult or laboured respiration)
- Abdominal discomfort
- Exfoliative rash (scaly red generalized skin rash)
- Feeling of body temperature change
- Rash erythematous (redness of the skin)
- Insomnia (sleeplessness)
- Myalgia (muscle pain)
- Burning sensation
What are the common drug interactions of Orenitram and Clopidogrel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Pain in extremity
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Pain
- Dizziness
- Anaemia (lack of blood)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood iron decreased
- Brain natriuretic peptide increased
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 23 people, 69.70%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 21.21%
- Pain: 4 people, 12.12%
- Hypotension (abnormally low blood pressure): 4 people, 12.12%
- Herpes Zoster: 4 people, 12.12%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.12%
- Gastric Ph Increased: 4 people, 12.12%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 12.12%
* Approximation only. Some reports may have incomplete information.
Do you take Orenitram and Clopidogrel?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Orenitram (17,714 reports)
- Clopidogrel (92,160 reports)
Browse all drug interactions of Orenitram and Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Orenitram:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Orenitram and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopidogrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on treprostinil and clopidogrel (the active ingredients of Orenitram and Clopidogrel, respectively), and Orenitram and Clopidogrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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