Ortho evra and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ortho evra (ethinyl estradiol; norelgestromin) and Abilify (aripiprazole). Common drug interactions include pulmonary embolism among females.

The phase IV clinical study analyzes what interactions people have when they take Ortho evra and Abilify. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Ortho evra?

Ortho evra has active ingredients of ethinyl estradiol; norelgestromin. It is often used in birth control. eHealthMe is studying from 29,275 Ortho evra users. Check the latest studies of Ortho evra.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,455 Abilify users. Check the latest studies of Abilify.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 25, 2026

31 people who take Ortho evra and Abilify together, and have interactions are studied.

Ortho evra and Abilify drug interactions.

What are the common drug interactions of Ortho Evra and Abilify, by gender? *:

female:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Delirium (wild excitement)
  3. Neuropathy peripheral (surface nerve damage)
  4. Dizziness
  5. Blood glucose decreased
  6. Drug ineffective
  7. Facial bones fracture (bone fracture of face)
  8. Fall
  9. Glycosylated haemoglobin increased
  10. Hepatic steatosis (fatty liver disease)

male:

n/a

What are the common drug interactions of Ortho Evra and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Delirium (wild excitement)
  2. Hallucination, auditory (perceiving sounds without auditory stimulus)
  3. Abortion (termination of pregnancy)
  4. Pregnancy on contraceptive
  5. Maternal exposure during pregnancy (use of substance during pregnancy)
  6. Anxiety
  7. Emotional distress
  8. Injury
  9. Pain
  10. Psychological trauma

30-39:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Apnoea (suspension of external breathing)
  3. Bradycardia (abnormally slow heart action)
  4. Cardiac arrest
  5. Dilatation ventricular
  6. Dizziness
  7. Facial bones fracture (bone fracture of face)
  8. Fall
  9. Injection site haemorrhage (bleeding from injection site)
  10. Loss of consciousness

40-49:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Anxiety
  3. Epstein-barr virus infection
  4. Fatigue (feeling of tiredness)
  5. Gout (uric acid crystals building up in the body)
  6. Neuropathy peripheral (surface nerve damage)
  7. Vomiting
  8. Metrorrhagia (uterine bleeding at irregular intervals)
  9. Drug ineffective
  10. Hepatic steatosis (fatty liver disease)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 29.03%
  2. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 6 people, 19.35%
  3. Premenstrual Syndrome: 2 people, 6.45%
  4. Panic Disorder: 2 people, 6.45%
  5. Bipolar Disorder (mood disorder): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ortho evra and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ortho evra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ortho evra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norelgestromin and aripiprazole (the active ingredients of Ortho evra and Abilify, respectively), and Ortho evra and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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