Oxycodone hydrochloride and Afinitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Afinitor (everolimus). Common drug interactions include impaired gastric emptying among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Afinitor. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

24 people who take Oxycodone hydrochloride and Afinitor together, and have interactions are studied.

Oxycodone hydrochloride and Afinitor drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Afinitor, by gender? *:

female:

Impaired gastric emptying
Influenza
Influenza like illness
Injury
Insomnia (sleeplessness)
Ligament sprain (ligament stretched)
Lipid metabolism disorder (genetic disorders are caused by errors in fatty acid metabolism)
Lymphadenopathy (disease or enlargement of lymph nodes)
Mass
Mediastinal mass (mass in the part of the chest that separates the lungs)

male:

Cardiac failure
Aphasia (damage to the parts of the brain that control language)
Feeding disorder (when children refuse to eat certain food groups)
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glossodynia (a burning or painful sensation in the tongue)
Headache (pain in head)
Hepatic mass
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)

What are the common drug interactions of Oxycodone Hydrochloride and Afinitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hospitalisation

50-59:

Haematuria (presence of blood in urine)
Hepatic steatosis (fatty liver disease)
High density lipoprotein decreased
Hot flush (sudden feelings of heat)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoxia (low oxygen in tissues)
Impaired gastric emptying

60+:

Cardiac failure
Nausea (feeling of having an urge to vomit)
Dehydration (dryness resulting from the removal of water)
Depressed level of consciousness
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Gait disturbance
Generalised oedema (swelling all over the body)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 7 people, 29.17%
Metastases To Lung (cancer spreads to lung): 3 people, 12.50%
Carcinoid Tumor: 3 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
Heart Disease: 2 people, 8.33%
Breast Cancer: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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