Oxycodone hydrochloride and Xtampza er drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone hydrochloride (oxycodone hydrochloride) and Xtampza er (oxycodone). Common drug interactions include quadriplegia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone hydrochloride and Xtampza er. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

What is Xtampza er?

Xtampza er has active ingredients of oxycodone. eHealthMe is studying from 1,502 Xtampza er users. Check the latest studies of Xtampza er.

On Jul, 11, 2026

37 people who take Oxycodone hydrochloride and Xtampza er together, and have interactions are studied.

Oxycodone hydrochloride and Xtampza er drug interactions.

What are the common drug interactions of Oxycodone Hydrochloride and Xtampza Er, by gender? *:

female:

Quadriplegia (a four limb paralysis)
Radiation associated pain (pain due to radiation)
Rib fracture
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swelling face
Ventricular extrasystoles (premature cardiac contraction)
Malaise (a feeling of general discomfort or uneasiness)
Arthralgia (joint pain)
Fall

male:

Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood calcium increased
Blood pressure increased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiomyopathy (weakening of the heart muscle)
Chest pain
Chills (felling of cold)
Confusional state

What are the common drug interactions of Oxycodone Hydrochloride and Xtampza Er, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Breakthrough pain
Feeling jittery
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Acute chest syndrome (acute chest pain, fever and difficulty breathing)
Arthralgia (joint pain)
Death
Headache (pain in head)
Hot flush (sudden feelings of heat)

50-59:

Blindness
Breast pain
Gastrointestinal motility disorder (abnormal intestinal contractions)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Oxygen saturation decreased
Quadriplegia (a four limb paralysis)
Radiation associated pain (pain due to radiation)
Respiratory tract infection

60+:

Arthralgia (joint pain)
Fall
Fatigue (feeling of tiredness)
Fungal skin infection
Small intestinal obstruction (blockage in small intestine)
Upper respiratory tract infection
Laryngeal discomfort
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Dizziness
Abdominal pain upper

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 13.51%
Multiple Myeloma (cancer of the plasma cells): 5 people, 13.51%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 13.51%
Drowsiness: 4 people, 10.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.11%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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