Oxycodone and Effient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Oxycodone (oxycodone hydrochloride) and Effient (prasugrel hydrochloride). Common drug interactions include dyspnoea among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Oxycodone and Effient. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.



On Jul, 14, 2026

99 people who take Oxycodone and Effient together, and have interactions are studied.

Oxycodone and Effient drug interactions.

What are the common drug interactions of Oxycodone and Effient, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Fibula fracture
  4. Pain in extremity
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Angina pectoris (chest pain due to ischemia of the heart muscle)
  7. Ankle fracture
  8. Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
  9. Blood pressure increased
  10. Bone density decreased

male:

  1. Chronic kidney disease
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Flushing (the warm, red condition of human skin)
  4. Dizziness
  5. Gait disturbance
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Nausea (feeling of having an urge to vomit)
  8. Pain in extremity
  9. Peripheral swelling
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Oxycodone and Effient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Muscle spasms (muscle contraction)

40-49:

  1. Chronic kidney disease
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Anxiety
  6. Chest pain
  7. Depression
  8. Dyspnoea (difficult or laboured respiration)
  9. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  10. Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

  1. Anxiety
  2. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  3. Arteriovenous fistula
  4. Asthenia (weakness)
  5. Blood pressure diastolic decreased
  6. Blood pressure diastolic increased
  7. Blood pressure systolic increased
  8. Bone density decreased
  9. Bradycardia (abnormally slow heart action)
  10. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)

60+:

  1. Chronic kidney disease
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Large intestinal ulcer haemorrhage (bleeding from large intestine ulcer)
  4. Nausea (feeling of having an urge to vomit)
  5. Renal disorder (kidney disease)
  6. Renal injury (kidney injury)
  7. Anaemia (lack of blood)
  8. Cardiac disorder
  9. Dizziness
  10. Drooling (drop saliva uncontrollably from the mouth)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 29 people, 29.29%
  2. High Blood Cholesterol: 20 people, 20.20%
  3. High Blood Pressure: 19 people, 19.19%
  4. Depression: 13 people, 13.13%
  5. Hiv Infection: 8 people, 8.08%
  6. Asthma: 8 people, 8.08%
  7. Insomnia (sleeplessness): 7 people, 7.07%
  8. Diabetes: 7 people, 7.07%
  9. Cardiac Disorder: 7 people, 7.07%
  10. Stress And Anxiety: 7 people, 7.07%

* Approximation only. Some reports may have incomplete information.

Do you take Oxycodone and Effient?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Oxycodone and Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oxycodone hydrochloride and prasugrel hydrochloride (the active ingredients of Oxycodone and Effient, respectively), and Oxycodone and Effient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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